Evidence map›Paper›PMID 34250249›Full record

ArticleOpen medicine (Warsaw, Poland)2021

Effects of hydroxyethyl starch and gelatin on the risk of acute kidney injury following orthotopic liver transplantation: A multicenter retrospective comparative clinical study.

Yingqi Chen, Xinyu Ning, Haiyang Lu, Sainan Zhu, Anshi Wu, Jia Jiang, Shanshan Mu, Jing Wang, Xu Niu, Shengnan Li and 9 more

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 1 country.

Yingqi ChenDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Xinyu NingDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Haiyang LuDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Sainan ZhuDepartment of Biostatistics, Peking University First Hospital, Beijing, 100034, China.
Anshi WuDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Jia JiangDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Shanshan MuDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Jing WangDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Xu NiuDepartment of Anesthesiology, The Third Medical Centre, Chinese People's Liberation Army General Hospital, No. 69 Yongding Road, Haidian District, Beijing, 100000, China.
Shengnan LiDepartment of Anesthesiology, The Third Medical Centre, Chinese People's Liberation Army General Hospital, No. 69 Yongding Road, Haidian District, Beijing, 100000, China.
Lingdi HouDepartment of Anesthesiology, The Third Medical Centre, Chinese People's Liberation Army General Hospital, No. 69 Yongding Road, Haidian District, Beijing, 100000, China.
Yanxing ZhaoDepartment of Anesthesiology, Beijing You'An Hospital, Capital Medical University, No. 8 Xitou Road, You'an Menwai, Fengtai District, Beijing, 100069, China.
Wenfei LvDepartment of Anesthesiology, Beijing You'An Hospital, Capital Medical University, No. 8 Xitou Road, You'an Menwai, Fengtai District, Beijing, 100069, China.
Meixia ShangDepartment of Biostatistics, Peking University First Hospital, Beijing, 100034, China.
Chen YaoDepartment of Biostatistics, Peking University First Hospital, Beijing, 100034, China.
Shujun HanDepartment of Anesthesiology, The Third Medical Centre, Chinese People's Liberation Army General Hospital, No. 69 Yongding Road, Haidian District, Beijing, 100000, China.
Ping ChiDepartment of Anesthesiology, Beijing You'An Hospital, Capital Medical University, No. 8 Xitou Road, You'an Menwai, Fengtai District, Beijing, 100069, China.
Fushan XueDepartment of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing, 100000, China.
Yun YueDepartment of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Beijing Chaoyang Emergency Medical Center · CNHainan Branch of People's Liberation Army General Hospital · CNBeijing YouAn Hospital · CNCapital Medical University · CNChinese People's Liberation Army · CNPeking University First Hospital · CNBeijing Friendship Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis multicenter retrospective study aimed to compare the effects of HES and gelatin (GEL) on the risk of post-OLT AKI.

methodA total of 1,672 patients undergoing OLT were enrolled from major transplant centers in China between 2005 and 2013. These patients were divided into three groups: GEL, hydroxyethyl starch (HES), and GEL + HES group.

resultsThere was no significant difference in the incidence of post-OLT AKI among the GEL, HES, and GEL + HES groups. The GEL + HES group had a lower incidence of stage II post-OLT AKI than the other two groups. Compared with patients receiving GEL, patients receiving HES did not harbor an increased risk of AKI. Our results showed that MELD score (adjusted odds ratio [OR], 1.579; 95% confidence interval [CI], 1.123-2.219;

conclusionThis large-scale multicenter retrospective study found that the intraoperative use of HES did not increase the overall incidence of post-OLT AKI in patients when compared with GEL, and whether to increase the risk of post-OLT AKI needs to be further explored.

Indexed as

acute kidney injurygelatinhydroxyethyl starchliver transplantationrisk factors

Identifiers

PMID34250249
PMCPMC8256391
OpenAlexW3135822894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.