Evidence map›Paper›PMID 34250153›Full record

ArticleOrthopaedic journal of sports medicine2021

Metrics of OsteoChondral Allografts (MOCA) Group Consensus Statements on the Use of Viable Osteochondral Allograft.

Simon Görtz, Suzanne M Tabbaa, Deryk G Jones, John D Polousky, Dennis C Crawford, MOCA Committee, William D Bugbee, Brian J Cole, Jack Farr, James E Fleischli and 16 more

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Simon GörtzBrigham and Women's Hospital, Boston, Massachusetts, USA.
Suzanne M TabbaaUniversity of California-San Francisco, San Francisco, California, USA.
Deryk G JonesOchsner Sports Medicine Institute, Jefferson, Louisiana, USA.
John D PolouskyChildren's Health Andrews Institute for Orthopedics and Sports Medicine, Plano, Texas, USA.
Dennis C CrawfordOregon Health and Science University, Portland, Oregon, USA.
MOCA Committee
William D BugbeeBrigham and Women's Hospital, Boston, Massachusetts, USA.
Brian J ColeBrigham and Women's Hospital, Boston, Massachusetts, USA.
Jack FarrBrigham and Women's Hospital, Boston, Massachusetts, USA.
James E FleischliBrigham and Women's Hospital, Boston, Massachusetts, USA.
Alan GetgoodBrigham and Women's Hospital, Boston, Massachusetts, USA.
Andreas H GomollBrigham and Women's Hospital, Boston, Massachusetts, USA.
Allan E GrossBrigham and Women's Hospital, Boston, Massachusetts, USA.
Aaron J KrychBrigham and Women's Hospital, Boston, Massachusetts, USA.
Christian LattermannBrigham and Women's Hospital, Boston, Massachusetts, USA.
Bert R MandelbaumBrigham and Women's Hospital, Boston, Massachusetts, USA.
Peter R MandtBrigham and Women's Hospital, Boston, Massachusetts, USA.
Raffy MirzayanBrigham and Women's Hospital, Boston, Massachusetts, USA.
Timothy S MologneBrigham and Women's Hospital, Boston, Massachusetts, USA.
Matthew T ProvencherBrigham and Women's Hospital, Boston, Massachusetts, USA.
Scott A RodeoBrigham and Women's Hospital, Boston, Massachusetts, USA.
Oleg SafirBrigham and Women's Hospital, Boston, Massachusetts, USA.
Eric D StraussBrigham and Women's Hospital, Boston, Massachusetts, USA.
Christopher J WahlBrigham and Women's Hospital, Boston, Massachusetts, USA.
Riley J WilliamsBrigham and Women's Hospital, Boston, Massachusetts, USA.
Adam B YankeBrigham and Women's Hospital, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteochondral allograft (OCA) transplantation has evolved into a first-line treatment for large chondral and osteochondral defects, aided by advancements in storage protocols and a growing body of clinical evidence supporting successful clinical outcomes and long-term survivorship. Despite the body of literature supporting OCAs, there still remains controversy and debate in the surgical application of OCA, especially where high-level evidence is lacking. PURPOSE: To develop consensus among an expert group with extensive clinical and scientific experience in OCA, addressing controversies in the treatment of chondral and osteochondral defects with OCA transplantation. STUDY

designConsensus statement.

methodsA focus group of clinical experts on OCA cartilage restoration participated in a 3-round modified Delphi process to generate a list of statements and establish consensus. Questions and statements were initially developed on specific topics that lack scientific evidence and lead to debate and controversy in the clinical community. In-person discussion occurred where statements were not agreed on after 2 rounds of voting. After final voting, the percentage of agreement and level of consensus were characterized. A systematic literature review was performed, and the level of evidence and grade were established for each statement.

resultsSeventeen statements spanning surgical technique, graft matching, indications, and rehabilitation reached consensus after the final round of voting. Of the 17 statements that reached consensus, 11 received unanimous (100%) agreement, and 6 received strong (80%-99%) agreement.

conclusionThe outcomes of this study led to the establishment of consensus statements that provide guidance on surgical and perioperative management of OCAs. The findings also provided insights on topics requiring more research or high-quality studies to further establish consensus and provide stronger evidence.

Indexed as

allograftsarticular cartilageosteochondral allograftosteochondritis dissecans

Identifiers

PMID34250153
PMCPMC8237219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.