ArticleFrontiers in veterinary science2021
Whole Genome or Single Genes? A Phylodynamic and Bibliometric Analysis of PRRSV.
Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bibliometric analysis of genomic selection in breeding of animal from 1993 to 2024: global trends and advancements.Frontiers in genetics · 2024Pooled it
- The genomic diversity of arthropod-specific viruses reinforces the continental distribution pattern of Aedes aegypti.Parasites & vectors · 2025Article
- In Vitro Characterization of Vaccine Strain-like Porcine Reproductive and Respiratory Syndrome Virus Strains Isolated from Weaned Pigs Exhibiting Respiratory Symptoms.Pathogens (Basel, Switzerland) · 2025Article
- Genetic variation in NSP4 of type 1 porcine reproductive and respiratory syndrome virus in China.BMC veterinary research · 2025Article
- The emergence and circulation of human immunodeficiency virus (HIV)-1 subtype C.Journal of medical microbiology · 2024Article
- Predicting Potential PRRSV-2 Variant Emergence through Phylogenetic Inference.Transboundary and emerging diseases · 2024Article
- Unveiling invisible farm-to-farm PRRSV-2 transmission links and routes through transmission tree and network analysis.Evolutionary applications · 2023Article
- First Detection of NADC34-like PRRSV as a Main Epidemic Strain on a Large Farm in China.Pathogens (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diversity, ecology, and evolution of viruses are commonly determined through phylogenetics, an accurate tool for the identification and study of lineages with different pathological characteristics within the same species. In the case of PRRSV, evolutionary research has divided into two main branches based on the use of a specific gene (i.e., ORF5) or whole genome sequences as the input used to produce the phylogeny. In this study, we performed a review on PRRSV phylogenetic literature and characterized the spatiotemporal trends in research of single gene vs. whole genome evolutionary approaches. Finally, using publicly available data, we produced a Bayesian phylodynamic analysis following each research branch and compared the results to determine the pros and cons of each particular approach. This study provides an exploration of the two main phylogenetic research lines applied for PRRSV evolution, as well as an example of the differences found when both methods are applied to the same database. We expect that our results will serve as a guidance for future PRRSV phylogenetic research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.