Evidence map›Paper›PMID 34250034›Full record

ArticleFrontiers in cardiovascular medicine2021

Methylenetetrahydrofolate Reductase Gene

Song Leng, Ai Zhao, Jian Zhang, Wei Wu, Qian Wang, Shan Wu, Li Chen, Qiang Zeng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Development of a Prognostic Model for MACE in Atherosclerosis Based on MTHFR and Serum Markers.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Song LengHealth Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army General Hospital, Beijing, China.
Ai ZhaoVanke School of Public Health, Tsinghua University, Beijing, China.
Jian ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Wei WuDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Qian WangHealth Management Center, The Second Hospital of Dalian Medical University, Dalian, China.
Shan WuHealth Management Center, The Second Hospital of Dalian Medical University, Dalian, China.
Li ChenHealth Management Center, The Second Hospital of Dalian Medical University, Dalian, China.
Qiang ZengHealth Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army General Hospital, Beijing, China.
Chinese People's Liberation Army · CNPeking University · CNSecond Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dietary patternhyperhomocysteinemiainteractionmethylenetetrahydrofolate reductaseMTHFR C677T

Identifiers

PMID34250034
PMCPMC8263928
OpenAlexW3195933526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.