Evidence map›Paper›PMID 34250031›Full record

ArticleCase reports in nephrology and dialysis

Immunotactoid Glomerulopathy with Nontuberculous Mycobacterial Infection: A Novel Association.

Yoshio Shimizu, Keiichi Wakabayashi, Hiroyuki Iwasaki, Chiaki Kishida, Sayaka Seki, Teruyuki Okuma, Naoko Iwakami, Takumi Iwasawa, Hiroshi Maekawa, Yasuhiko Tomino and 2 more

Abstract readCase Reports
In one paragraph

Article in Case reports in nephrology and dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Immunotactoid glomerulopathy in rheumatoid arthritis.Clinical nephrology. Case studies · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yoshio ShimizuDivision of Nephrology, Department of Internal Medicine, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Keiichi WakabayashiDivision of Nephrology, Department of Internal Medicine, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Hiroyuki IwasakiDivision of Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Chiaki KishidaDivision of Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Sayaka SekiDivision of Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Teruyuki OkumaDivision of Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Naoko IwakamiDivision of Respiratory Medicine, Department of Internal Medicine, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Takumi IwasawaShizuoka Medical Research Center for Disaster, Juntendo University, Izunokuni, Japan.
Hiroshi MaekawaDepartment of Surgery, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Yasuhiko TominoAsian Pacific Renal Research Promotion Office, Medical Corporation SHOWAKI, Tokyo, Japan.
Ryo WadaDivision of Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Yusuke SuzukiDepartment of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old woman underwent a renal biopsy due to nephrotic syndrome. She had suffered from nontuberculous mycobacterial infection (NTM) for 14 years. The patient was diagnosed as having membranoproliferative glomerulonephritis (MPGN) type 3 and immunoglobulin (Ig)-associated MPGN based upon LM/erythromycin and IF findings, respectively. In high-magnification imaging, electron-dense deposits showed immunotactoid glomerulopathy (ITG). There was no evidence of hematological cancer, and the patient improved after receiving treatments for NTM. To the best of our knowledge, this patient is the first to show an association between ITG and NTM. Although ITG is generally considered as related to lymphoproliferative disease, it is suggested that ITG is driven by bacterial infection and is a potential outcome of Ig-associated MPGN.

Indexed as

Immunotactoid glomerulopathyMPGN type 3Nontuberculous mycobacterial infectionNovel classification of MPGN

Identifiers

PMID34250031
PMCPMC8255749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.