Evidence map›Paper›PMID 34250016›Full record

ReviewFrontiers in molecular biosciences2021

The Role of Human Papilloma Virus in Dictating Outcomes in Head and Neck Squamous Cell Carcinoma.

Shane Brennan, Anne-Marie Baird, Esther O'Regan, Orla Sheils

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Cancer-AssociatedInternational journal of medical sciences · 2025
    Review
  7. Review
  8. HPV-related diseases in male patients: an underestimated conundrum.Journal of endocrinological investigation · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shane BrennanSchool of Medicine, Faculty of Health Sciences, Trinity College, Dublin, Ireland.
Anne-Marie BairdSchool of Medicine, Faculty of Health Sciences, Trinity College, Dublin, Ireland.
Esther O'ReganDepartment of Histopathology, St. James's Hospital, Dublin, Ireland.
Orla SheilsSchool of Medicine, Faculty of Health Sciences, Trinity College, Dublin, Ireland.
Trinity College Dublin · IESt. James's Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Human Papilloma Virus (HPV) is an oncogenic virus which is associated with the development of head and neck squamous cell carcinoma (HNSCC), predominantly within the oropharynx. Approximately 25% of oropharyngeal squamous cell carcinoma (OPSCC) cases worldwide are attributable to HPV infection, with an estimated 65% in the United States. Transmission is

Indexed as

cancer recurrence and metastasishead and neck cancerHPV genotypeHPV—human papillomavirusoropharyngeal cancersomatic mutation analysis

Identifiers

PMID34250016
PMCPMC8262095
OpenAlexW3175503108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.