Evidence map›Paper›PMID 34249966›Full record

ArticleFrontiers in medicine2021

Urethral Catheter Biofilms Reveal Plasticity in Bacterial Composition and Metabolism and Withstand Host Immune Defenses in Hypoxic Environment.

Yanbao Yu, Harinder Singh, Tamara Tsitrin, Shiferaw Bekele, Yi-Han Lin, Patricia Sikorski, Kelvin J Moncera, Manolito G Torralba, Lisa Morrow, Randall Wolcott and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. CAUTIon - not all UTIs are the same.Nature reviews. Urology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yanbao YuJ. Craig Venter Institute, Rockville, MD, United States.
Harinder SinghJ. Craig Venter Institute, Rockville, MD, United States.
Tamara TsitrinJ. Craig Venter Institute, Rockville, MD, United States.
Shiferaw BekeleJ. Craig Venter Institute, Rockville, MD, United States.
Yi-Han LinJ. Craig Venter Institute, Rockville, MD, United States.
Patricia SikorskiJ. Craig Venter Institute, Rockville, MD, United States.
Kelvin J MonceraJ. Craig Venter Institute, La Jolla, CA, United States.
Manolito G TorralbaJ. Craig Venter Institute, La Jolla, CA, United States.
Lisa MorrowSouthwest Regional Wound Care Center, Lubbock, TX, United States.
Randall WolcottSouthwest Regional Wound Care Center, Lubbock, TX, United States.
Karen E NelsonJ. Craig Venter Institute, Rockville, MD, United States.
Rembert PieperJ. Craig Venter Institute, Rockville, MD, United States.
J. Craig Venter Institute · USSouthwest Regional Wound Care Center · US

Funding

Urethral Catheter-Associated Polybacterial Biofilm Formation and DispersalR01GM103598 · NIGMS · J. CRAIG VENTER INSTITUTE, INC. · PI PIEPER, REMBERT · 2013 to 2016
$1.3M
NIGMS NIH HHS R01 GM103598
6 · The paper itself

Abstract

Biofilms composed of multiple microorganisms colonize the surfaces of indwelling urethral catheters that are used serially by neurogenic bladder patients and cause chronic infections. Well-adapted pathogens in this niche are

Indexed as

bacterial metabolismcatheter biofilmimmune defenseinfectionpathogenpolymicrobialproteomics

Identifiers

PMID34249966
PMCPMC8260951
OpenAlexW3173920605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.