ReviewFrontiers in chemistry2021
Recent Advances in Cyanine-Based Phototherapy Agents.
Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 75 citations in OpenAlex.
- Reprogramming Photodynamic Therapy with BODIPY Photosensitizers: From Local Phototoxicity Toward Precision Photodynamic Oncology.Molecules (Basel, Switzerland) · 2026Review
- Leucine Aminopeptidase-Activatable Photosensitizer Enables Enzyme-Responsive Photodynamic Therapy in Neuroblastoma.ACS omega · 2026Article
- Molecular design and excited state dynamics regulation in phototheranostics.Biophysics reports · 2025Article
- Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors.Journal of nanobiotechnology · 2025Article
- Aggregation control of anionic pentamethine cyanine enabling excitation wavelength selective NIR-II fluorescence imaging-guided photodynamic therapy.Nature communications · 2025Article
- Recent progresses in combination cancer therapy using cyanine dye-based nanoparticles.Pharmaceutical science advances · 2024Review
- A New Demand for Improved Selectivity and Potency of Cyanine Dyes as Antiproliferative Agents Against Colorectal Cancer Cells.Molecules (Basel, Switzerland) · 2024Article
- Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy.Communications chemistry · 2024Review
- Near-infrared photocatalysis with cyanines: synthesis, applications and perspectives.Chemical science · 2024Review
- Molecular jackhammers eradicate cancer cells by vibronic-driven action.Nature chemistry · 2024Article
- Toxic Effects of Penetrating Cations.Membranes · 2023Review
- Hydrogen Sulfide Responsive Phototherapy Agents: Design Strategies and Biological Applications.ACS bio & med chem Au · 2023Review
- Aggregates of Cyanine Dyes: When Molecular Vibrations and Electrostatic Screening Make the Difference.The journal of physical chemistry. C, Nanomaterials and interfaces · 2023Article
- Image-Guided Enhanced PDT/PTT Combination Therapy Using Brominated Hemicyanine-Loaded Folate Receptor-Targeting AgBioconjugate chemistry · 2023Article
- Recent Developments in Nanoparticle-Based Photo-Immunotherapy for Cancer Treatment.Small methods · 2023Review
- BOINPYs: facile synthesis and photothermal properties triggered by photoinduced nonadiabatic decay.Chemical science · 2023Article
- Effect of Solubilizing Group on the Antibacterial Activity of Heptamethine Cyanine Photosensitizers.Pharmaceutics · 2023Article
- Fluorophore-mediated Photooxidation of the Guanine Heterocycle.Journal of physical organic chemistry · 2022Article
- Photonics of Trimethine Cyanine Dyes as Probes for Biomolecules.Molecules (Basel, Switzerland) · 2022Review
- An Insight into Symmetrical Cyanine Dyes as Promising Selective Antiproliferative Agents in Caco-2 Colorectal Cancer Cells.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phototherapies, in the form of photodynamic therapy (PDT) and photothermal therapy (PTT), are very promising treatment modalities for cancer since they provide locality and turn-on mechanism for toxicity, both of which are critical in reducing off-site toxicity. Irradiation of photosensitive agents demonstrated successful therapeutic outcomes; however, each approach has its limitations and needs to be improved for clinical success. The combination of PTT and PDT may work in a synergistic way to overcome the limitations of each method and indeed improve the treatment efficacy. The development of single photosensitive agents capable of inducing both PDT and PTT is, therefore, extremely advantageous and highly desired. Cyanine dyes are shown to have such potential, hence have been very popular in the recent years. Luminescence of cyanine dyes renders them as phototheranostic molecules, reporting the localization of the photosensitive agent prior to irradiation to induce phototoxicity, hence allowing image-guided phototherapy. In this review, we mainly focus on the cyanine dye-based phototherapy of different cancer cells, concentrating on the advancements achieved in the last ten years.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.