Evidence map›Paper›PMID 34249867›Full record

ArticleFrontiers in chemistry2021

Optimized MALDI-TOF MS Strategy for Characterizing Polymers.

Zhenxin Wang, Quanqing Zhang, Huali Shen, Pengyuan Yang, Xinwen Zhou

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Microwave-Driven Cytocompatible Mn-Doped TiOACS applied materials & interfaces · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Quantitative mass spectrometry imaging: therapeutics & biomolecules.Chemical communications (Cambridge, England) · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenxin WangInstitutes of Biomedical Sciences of Shanghai Medical School and Laboratory Medicine of Zhongshan Hospital, Fudan University, Shanghai, China.
Quanqing ZhangDepartment of Chemistry, University of California, Riverside, CA, United States.
Huali ShenInstitutes of Biomedical Sciences of Shanghai Medical School and Minhang Hospital, Fudan University, Shanghai, China.
Pengyuan YangInstitutes of Biomedical Sciences of Shanghai Medical School and Department of Chemistry, Fudan University, Shanghai, China.
Xinwen ZhouInstitutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) plays an essential role in the analysis of polymers. To acquire a more reliable strategy for polymer profiling, we characterized four representative polymers including polyethylene glycol 6000, polyvinylpyrrolidone K12, polymer polyol KPOP-5040, and polyether polyol DL-4000. The preparation methods of these four polymer samples have been optimized from six aspects, including matrix, cationization reagent, solvent, mixing ratio of cationization reagent to polymer, mixing ratio of matrix to polymer, and laser intensity. After investigating the effects of seven commonly used matrices on the ionization efficiency of four polymers,

Indexed as

MALDI-TOF MSpolyether polyol DL-4000polyethylene glycol 6000polymerpolymer polyol KPOP-5040polyvinylpyrrolidone K12

Identifiers

PMID34249867
PMCPMC8264446

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.