Evidence map›Paper›PMID 34249803›Full record

ArticleFrontiers in pediatrics2021

Prevention of Neural Tube Defects in Europe: A Public Health Failure.

Joan K Morris, Marie-Claude Addor, Elisa Ballardini, Ingeborg Barisic, Laia Barrachina-Bonet, Paula Braz, Clara Cavero-Carbonell, Elly Den Hond, Ester Garne, Miriam Gatt and 23 more

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
  5. Awareness and Use of Folic Acid Among Pregnant Women in Western Ukraine: A Pilot Study.International journal of environmental research and public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Joan K MorrisPopulation Health Research Institute, St. George's, University of London, London, United Kingdom.
Marie-Claude AddorDepartment of Woman-Mother-Child, University Hospital Center, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Elisa BallardiniIndagine Sulle Malformazioni Congenite in Emilia-Romagna (IMER) Registry (Emilia Romagna Registry of Birth Defects) Neonatal Intensive Care Unit, Pediatric Section Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Ingeborg BarisicCentre of Excellence for Reproductive and Regenerative Medicine, Children's Hospital Zagreb, Medical School University of Zagreb, Zagreb, Croatia.
Laia Barrachina-BonetRare Diseases Research Unit, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, Valencia, Spain.
Paula BrazEpidemiology Department, National Institute of Health Doutor Ricardo Jorge, Lisboa, Portugal.
Clara Cavero-CarbonellRare Diseases Research Unit, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, Valencia, Spain.
Elly Den HondHealth Department, Provincial Institute of Hygiene, Antwerp, Belgium.
Ester GarnePaediatric Department, Hospital Lillebaelt Kolding, Kolding, Denmark.
Miriam GattDirectorate for Health Information and Research, Pietà, Malta.
Martin HaeuslerDepartment of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria.
Babak KhoshnoodUniversité de Paris, Center of Research in Epidemiology and StatisticS/CRESS/Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé), INSERM, INRA, Paris, France.
Nathalie LelongUniversité de Paris, Center of Research in Epidemiology and StatisticS/CRESS/Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé), INSERM, INRA, Paris, France.
Agnieszka Kinsner-OvaskainenEuropean Commission, Joint Research Centre, Ispra, Italy.
Sonja Kiuru-KuhlefeltFinnish Institute for Health and Welfare Terveyden Ja Hyvinvoinnin Laitos (THL), Register of Congenital Malformations, Helsinki, Finland.
Kari KlungsoyrDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Anna Latos-BielenskaDepartment of Medical Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Elizabeth LimbPopulation Health Research Institute, St. George's, University of London, London, United Kingdom.
Mary T O'MahonyHealth Service Executive-South, Department of Public Health, St. Finbarr's Hospital, Cork, Ireland.
Isabelle PerthusAuvergne Registry of Congenital Anomalies (CEMC-Auvergne), Department of Clinical Genetics, Centre de Référence des Maladies Rares, CHU Estaing, Clermont-Ferrand, France.
Anna PieriniInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Judith RankinPopulation Health Sciences Institute, Newcastle University, Newcastle, United Kingdom.
Anke RissmannMalformation Monitoring Centre Saxony-Anhalt, Medical Faculty Otto-von-Guericke-University, Magdeburg, Germany.
Florence RougetBrittany Registry of Congenital Anomalies, CHU Rennes, Univ Rennes, INSERM, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France.
Gerardine SayersHealth Intelligence R&D Health Service Executive, Dublin, Ireland.
Antonin SipekDepartment of Medical Biology and Genetics, 1st Faculty of Medicine, General University Hospital, Charles University, Prague, Czechia.
Sarah StevensPublic Health England, London, United Kingdom.
David TuckerCongenital Anomaly Register and Information Service for Wales, Public Health Wales Knowledge Directorate, Singleton Hospital, Swansea, United Kingdom.
Christine Verellen-DumoulinCentre de Génétique Humaine, Institut de Pathologie et de Génétique, Charleroi, Belgium.
Hermien E K de WalleDepartment of Genetics, Eurocat Northern Netherlands, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Diana WellesleyWessex Clinical Genetics Service, Princess Anne Hospital, Southampton, United Kingdom.
Wladimir WerteleckiOMNI-Net Ukraine Programs, Rivne, Ukraine.
Eva Bermejo-SanchezSpanish Collaborative Study of Congenital Malformations (ECEMC), Unidad de Investigación sobre Anomalías Congénitas, Institute of Rare Diseases Research (IIER), Instituto de Salud Carlos III, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Europefolic acidfortificationneural tube defectsprevention

Identifiers

PMID34249803
PMCPMC8264257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.