Evidence map›Paper›PMID 34249782›Full record

ArticleFrontiers in cellular and infection microbiology2021

ATI-2307 Exhibits Equivalent Antifungal Activity in

Elliot S Gerlach, Sophie Altamirano, J Marina Yoder, Tony S Luggya, Andrew Akampurira, David B Meya, David R Boulware, Joshua Rhein, Kirsten Nielsen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Recent innovations and challenges in the treatment of fungal infections.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Review
  6. Cryptococcal meningitis.Nature reviews. Disease primers · 2023
    Review
  7. Article
  8. Review
  9. Pulmonary Cryptococcosis.Journal of fungi (Basel, Switzerland) · 2022
    Review
  10. Lack of Association between Fluconazole Susceptibility andJournal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Elliot S GerlachDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, United States.
Sophie AltamiranoDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, United States.
J Marina YoderDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, United States.
Tony S LuggyaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Andrew AkampuriraInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
David B MeyaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
David R BoulwareDivision of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Joshua RheinDivision of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Kirsten NielsenDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, United States.
University of Minnesota · USInfectious Diseases Institute · UGMakerere University · UG

Funding

Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisR01NS086312 · NINDS · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2013 to 2026
$8.3M
Trial for the Optimal Timing of HIV Therapy after Cryptococcal MeningitisU01AI089244 · NIAID · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R · 2010 to 2014
$7.6M
Training Research Educators in Minnesota (TREM) whilst increasing diversityK12GM119955 · NIGMS · UNIVERSITY OF MINNESOTA · PI David Irwin Greenstein, Julia Willett · 2017 to 2026
$6.5M
Genomic Research Capacity Building for Cryptococcosis Translational StudiesR01NS118538 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Joel Bazira, David Bisagaya Meya · 2020 to 2026
$3.4M
NIAID NIH HHS U01 AI089244NIGMS NIH HHS K12 GM119955NINDS NIH HHS R01 NS086312NINDS NIH HHS R01 NS118538
6 · The paper itself

Abstract

Half maximal inhibitory concentrations (IC

Indexed as

CryptococcosisCryptococcus neoformansAmphotericin BAntifungal AgentsDrug Resistance, FungalFluconazoleHumansMicrobial Sensitivity TestsAmphotericin BAntifungal AgentsFluconazoleantifungalATI-2307azoleCryptococcusIC50resistancesusceptibilityT-2307

Identifiers

PMID34249782
PMCPMC8262267
OpenAlexW3176651112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.