Evidence map›Paper›PMID 34249762›Full record

ArticleFrontiers in oncology2021

Case Report: Paclitaxel-Induced Pneumonitis in Early Breast Cancer: A Single Institution Experience and Review.

Luke Ardolino, Brandon Lau, Isabella Wilson, Julia Chen, Linda Borella, Emily Stone, Elgene Lim

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Drug-Induced Interstitial Lung Disease in Lung Cancer Patients.Respiration; international review of thoracic diseases · 2026
    Review
  6. Review
  7. Article
  8. Natural Taxanes: From Plant Composition to Human Pharmacology and Toxicity.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Luke ArdolinoDepartment of Medical Oncology, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Brandon LauDepartment of Medical Oncology, Fiona Stanley Hospital, Murdoch, Perth, WA, Australia.
Isabella WilsonDepartment of Medical Oncology, Crown Princess Mary Cancer Centre, Westmead, NSW, Australia.
Julia ChenDepartment of Medical Oncology, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Linda BorellaDepartment of Medical Oncology, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Emily StoneSt. Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia.
Elgene LimDepartment of Medical Oncology, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
St Vincent's Hospital Sydney · AUUNSW Sydney · AUFiona Stanley Hospital · AUGarvan Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taxane-based chemotherapy regimens are in widespread use as standard of care treatment for patients with early breast cancer, though rarely its use can be complicated by taxane-induced pneumonitis (TIP). While breast cancer is the most diagnosed cancer in women worldwide, TIP remains under-described in this setting. Key questions relate to its incidence, diagnosis and management, potential predictive biomarkers, and the balance between this life-threatening toxicity and curatively intended treatment. At a single Australian institution, 6 cases of TIP are identified among 132 patients treated with a paclitaxel-containing regimen for early breast cancer (4.55%, 95% confidence interval 1.69-9.63%). This review first outlines the presentation, management, and outcomes for these cases, then answers these questions and proposes an approach to suspected TIP in patients with breast cancer.

Indexed as

chemotherapyearly breast cancerimmunotherapymanagement of toxicitiespneumonitis and pulmonary toxicity

Identifiers

PMID34249762
PMCPMC8261280
OpenAlexW3176435250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.