Evidence map›Paper›PMID 34249748›Full record

ArticleFrontiers in oncology2021

Hao Wang, Wenwei Zhu, Shuhua Ren, Yanyan Kong, Qi Huang, Jun Zhao, Yihui Guan, Huliang Jia, Jinhong Chen, Lu Lu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Diagnostic Performance of Radiolabelled FAPI Versus [International journal of molecular sciences · 2025
    Pooled it
  2. Head-to-head comparison ofFrontiers in oncology · 2023
    Pooled it
  3. Comparison ofFrontiers in oncology · 2023
    Pooled it
  4. Pooled it
  5. Assessment of liver fibrosis and tumor burden in hepatocellular carcinoma using [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  6. Head-to-head study of [BMC cancer · 2024
    Trial
  7. Article
  8. [Scientific reports · 2026
    Article
  9. Diagnostic Efficacy of FAPI-PET/CT Versus [Diagnostics (Basel, Switzerland) · 2026
    Review
  10. Article
  11. Diagnostics (Basel, Switzerland) · 2026
    Article
  12. Review
  13. Review
  14. Review
  15. Correlations between Ki67 expression and uptake ofCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  16. Article
  17. Prognostic and diagnostic value of [European radiology · 2025
    Article
  18. Molecular imaging and biology · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hao WangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Wenwei ZhuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Shuhua RenPET Centre, Huashan Hospital, Fudan University, Shanghai, China.
Yanyan KongPET Centre, Huashan Hospital, Fudan University, Shanghai, China.
Qi HuangPET Centre, Huashan Hospital, Fudan University, Shanghai, China.
Jun ZhaoDepartment of Nuclear Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yihui GuanPET Centre, Huashan Hospital, Fudan University, Shanghai, China.
Huliang JiaDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jinhong ChenDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Lu LuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Fang XiePET Centre, Huashan Hospital, Fudan University, Shanghai, China.
Lunxiu QinDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Huashan Hospital · CNFudan University · CNShanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibroblast activation protein (FAP) is commonly expressed in activated stromal fibroblasts in various epithelial tumours. Recently, MATERIALS AND

methodsTwenty-nine patients with suspiciously HCC who received both

resultsA total of 35 intrahepatic lesions in 25 patients with HCC were finally involved in the statistical analysis.

conclusions

Indexed as

18F-FDG68Ga-FAPI-04cancer-associated fibroblast (CAF)fibroblast activating protein (FAP)hepatocellular carcinoma (HCC)

Identifiers

PMID34249748
PMCPMC8267923
OpenAlexW3173856189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.