Evidence map›Paper›PMID 34249653›Full record

ArticleQuantitative imaging in medicine and surgery2021

Research on the distribution spectrum of atherosclerotic plaques in patients with suspected coronary artery disease and the noninvasive screening model for coronary atherosclerosis burden.

Pengxi Han, Jinyan Tang, Ximing Wang, Yuwen Su, Guijie Li, Kai Deng

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pengxi HanDepartment of Radiology, the First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Jinyan TangDepartment of Pediatrics, Xiangxi Autonomous Prefecture People's Hospital, Jishou, China.
Ximing WangDepartment of Radiology, Shandong Provincial Hospital of Shandong First Medical University, Jinan, China.
Yuwen SuDepartment of Radiology, the First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Guijie LiDepartment of Interventional Radiology, the First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Kai DengDepartment of Radiology, the First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Shandong First Medical University · CNShandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to establish a non-invasive and simple screening model of coronary atherosclerosis burden based on the associations between multiple blood parameters and total plaque score (TPS), segment-stenosis score (SSS), coronary artery disease severity (CADS) in coronary artery disease (CAD) and thus reduce unnecessary coronary angiography (CAG).

methodsA total of 1,366 patients with suspected CAD who underwent CAG were included in this study. The clinical risk factors [age, gender, systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), high-density lipoprotein (HDL), triglyceride (TG), low-density lipoprotein (LDL), fasting plasma glucose (FPG), and glycated hemoglobin (GHB)] were collected. The presence of plaques and lumen stenosis was assessed based on CAG imaging. The TPS, SSS, and CADS were calculated, and the distribution spectrum of atherosclerotic plaques was described. Kruskal-Wallis test for multiple comparison tests was performed to analyze the differences in groups of different risk factors. The selected independent predictors were put into a multivariate logistic model, and the variables were further screened by stepwise regression to establish a screening model. Finally, the receiver operating characteristic (ROC) curve was used to evaluate the selected model's discriminant effect.

resultsThe distributions of TPS and SSS scores were both right-skewed. Among males, both TPS and SSS scores were higher than in females (χ

conclusionsThe most common site of lesions was P-LAD. These models can be used as non-invasive and simple initial screening tools without CAG.

Indexed as

coronary angiography (CAG)Coronary artery disease (CAD)non-invasive screening modelplaque distribution spectrum

Identifiers

PMID34249653
PMCPMC8250030
OpenAlexW3157621918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.