ArticleQuantitative imaging in medicine and surgery2021
Pilot case-control study to explore the value of intestinal ultrasound in the differentiation of two common diseases involving the ileocecal region: intestinal Behçet's disease and Crohn's disease.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 6 citations in OpenAlex.
- Development and validation of a novel intestinal ultrasound score for predicting endoscopic activity of ileocecal ulcers in intestinal Behçet's disease.Journal of gastroenterology · 2026Article
- Intestinal ultrasound for intestinal Behçet disease reflects endoscopic activity and histopathological findings.Intestinal research · 2024Article
- Enhancing the Differentiation between Intestinal Behçet's Disease and Crohn's Disease through Quantitative Computed Tomography Analysis.Bioengineering (Basel, Switzerland) · 2023Article
- A magnetic resonance enterography index for assessing small bowel Crohn's disease activity.Quantitative imaging in medicine and surgery · 2023Article
- The treatment principles and targets for intestinal Behcet's disease.Therapeutic advances in gastroenterology · 2023Review
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Authors and funding
7 authors at 3 institutions in 1 country.
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Abstract
backgroundIntestinal Behçet's disease (BD) and Crohn's disease (CD) are two diseases that commonly involve the ileocecal region and are difficult to differentiate. We aimed to investigate the value of intestinal ultrasound (IUS) in differentiating between these diseases.
methodsIn this case-control study, patients diagnosed with intestinal BD or CD in the ileocecal region involved were recruited. The IUS characteristics of the two disease groups in terms of disease location, ileocecal region characteristics, and complications were compared. The differences were analyzed using univariate and multivariate analyses.
resultsWe consecutively enrolled 22 intestinal BD and 44 age- and sex-matched CD patients. On univariate analysis, focal lesion, ileocecal region involvement only, presence of ulcers on ultrasound (US), large ulcers (>2 cm) on US, and fistulas were significantly more common in intestinal BD than in CD, whereas small intestine involvement was significantly more common in CD. On multivariate analysis, focal lesion [odds ratio (OR) 0.156, 95% confidence interval (CI): 0.043-0.564], and large ulcers (OR 0.056, 95% CI: 0.006-0.550) were independent predictors of intestinal BD over CD. The area under the curve for the receiver-operating characteristic was 0.808 (95% CI: 0.706-0.929), and the sensitivity and specificity with a cutoff value of 0.7 were 75.0% and 77.3%, respectively.
conclusionsIUS can provide useful information for the differential diagnosis of intestinal BD and CD.
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