Evidence map›Paper›PMID 34249593›Full record

Article3 Biotech2021

MicroRNA-199-3p targets Sp1 transcription factor to regulate proliferation and epithelial to mesenchymal transition of human lung cancer cells.

Jiajia Fu, Tong Li, Xiaozhen Jiang, Bin Xia, Lijuan Hu

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jiajia Fu *Department of Pulmonary Medicine, The Second People's Hospital of Yueqing, Zhejiang, 325608 China.
Tong Li *Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032 China.
Xiaozhen JiangDepartment of Pulmonary Medicine, PingYang Hospital Affiliated to Wenzhou Medical University, Zhenjiang, 325400 China.
Bin XiaDepartment of Pulmonary Medicine, The Second People's Hospital of Yueqing, Zhejiang, 325608 China.
Lijuan HuDepartment of Pulmonary Medicine, Zhongshan Hospital, Fudan University, No.180, Fenglin Road, Xuhui District, Shanghai, 200032 China.ORCID 0000-0003-1968-0897
Yueqing People's Hospital · CNFudan University · CNSun Yat-sen University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was undertaken to study the function of miRNA-199-3p in the regulation of human lung cancer growth and metastasis. The results showed significant (

Indexed as

Epithelial-to-mesenchymal transitionLung cancerMicro-RNAmiRNA-199-3pPost-transcriptional silencingSP1 transcription factor

Identifiers

PMID34249593
PMCPMC8219823
OpenAlexW3177436477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.