Evidence map›Paper›PMID 34249477›Full record

ArticleFatigue : biomedicine, health & behavior2021

Prediction of evening fatigue severity in outpatients receiving chemotherapy: less may be more.

Kord M Kober, Ritu Roy, Anand Dhruva, Yvette P Conley, Raymond J Chan, Bruce Cooper, Adam Olshen, Christine Miaskowski

Open access · bronzeAbstract read
In one paragraph

Article in Fatigue : biomedicine, health & behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Prediction of morning fatigue severity in outpatients receiving chemotherapy: less may still be more.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  7. [Tiredness, fatigue and exhaustion: all the same or manifestations of a continuum?-Food for thought].Somnologie : Schlafforschung und Schlafmedizin = Somnology : sleep research and sleep medicine · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kord M KoberSchool of Nursing, University of California, San Francisco, USA.ORCID 0000-0001-9732-3321
Ritu RoyHelen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.ORCID 0000-0003-2065-7846
Anand DhruvaSchool of Medicine, University of California, San Francisco, USA.ORCID 0000-0001-5552-7131
Yvette P ConleySchool of Nursing, University of Pittsburgh, Pittsburgh, USA.ORCID 0000-0002-1784-6067
Raymond J ChanSchool of Nursing and Cancer and Palliative Care Outcomes Centre, Queensland University of Technology, Kelvin Grove, Australia.ORCID 0000-0003-0248-7046
Bruce CooperSchool of Nursing, University of California, San Francisco, USA.
Adam OlshenHelen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.ORCID 0000-0002-8998-4514
Christine MiaskowskiSchool of Nursing, University of California, San Francisco, USA.ORCID 0000-0001-5170-2027
University of California, San Francisco · USQueensland University of Technology · AUUniversity of Pittsburgh · US

Funding

Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kate Taylor Shumate · 1999 to 2026
$209.7M
Symptoms Clusters in Oncology Patients Receiving ChemotherapyR01CA134900 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AOUIZERAT, BRADLEY E, MIASKOWSKI, CHRISTINE A. · 2009 to 2014
$5.9M
An Investigation of the Molecular Mechanisms for and Prediction of the Severity of Cancer Chemotherapy-Related Fatigue Using a Multi-staged Integrated Omics ApproachR37CA233774 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KOBER, KORD MICHAEL · 2019 to 2025
$4.8M
NCI NIH HHS P30 CA082103NCI NIH HHS R01 CA134900NCI NIH HHS R37 CA233774
6 · The paper itself

Abstract

backgroundFatigue is the most common and debilitating symptom experienced by oncology patients undergoing chemotherapy. Little is known about patient characteristics that predict changes in fatigue severity over time. PURPOSE: To predict the severity of evening fatigue in the week following the administration of chemotherapy using machine learning approaches.

methodsOutpatients with breast, gastrointestinal, gynecological, or lung cancer (

resultsRandom forest (RF) models provided the best fit across all models. For the RF model using individual LFS item scores, two of the 13 individual LFS items (i.e., "worn out", "exhausted") were the strongest predictors.

conclusionThis study is the first to use machine learning techniques to predict evening fatigue severity in the week following chemotherapy from fatigue scores obtained in the week prior to chemotherapy. Our findings suggest that the language used to assess clinical fatigue in oncology patients is important and that two simple questions may be used to predict evening fatigue severity.

Indexed as

cancerchemotherapyfatiguemachine learningpatient-reported outcomespredictive modelsymptoms

Identifiers

PMID34249477
PMCPMC8262130
OpenAlexW3130329074

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.