Evidence map›Paper›PMID 34249428›Full record

ArticleAmerican journal of cancer research2021

OX40 agonist combined with irreversible electroporation synergistically eradicates established tumors and drives systemic antitumor immune response in a syngeneic pancreatic cancer model.

Qi-Wei Zhang, Xiao-Xia Guo, Yu Zhou, Qing-Bing Wang, Qin Liu, Zhi-Yuan Wu, Xiao-Yi Ding

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qi-Wei ZhangDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Xiao-Xia GuoDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Yu ZhouDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Qing-Bing WangDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Qin LiuDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Zhi-Yuan WuDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Xiao-Yi DingDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine No. 197, Ruijin Er Road, Shanghai 200025, China.
Ruijin Hospital · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we intended to explore a novel combination treatment scheme for pancreatic cancer, using irreversible electroporation (IRE) and OX40 agonist. We further aimed to investigate the capacity and mechanism of this combination treatment using an

Indexed as

combination treatmentimmunotherapyirreversible electroporationOX40Pancreatic cancer

Identifiers

PMID34249428
PMCPMC8263674
OpenAlexW3179668330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.