Evidence map›Paper›PMID 34249290›Full record

ArticleRare tumors2021

A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer.

Anthony L Nguyen, Esther G Chong, Joanne Lee, Saied Mirshahidi, Hamid Mirshahidi

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Rare tumors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anthony L NguyenDivision of Medical Oncology and Hematology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Esther G ChongDepartment of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.ORCID https://orcid.org/0000-0002-0508-9521
Joanne LeeLoma Linda University School of Medicine, Loma Linda, CA, USA.
Saied MirshahidiLoma Linda University Cancer Center Biospecimen Laboratory, Department of Microbiology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Hamid MirshahidiDivision of Medical Oncology and Hematology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Loma Linda University Medical Center · USLoma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous metastasis of breast cancer carries a poor prognosis, invokes a poor quality of life, and increases mortality by raising one's risk of bleeding and infection. Currently, options for treatment are systemic chemotherapy, surgical resection and radiation. These treatments are invasive and can have toxic side effects. A 50-year-old African-American woman with stage IV breast cancer with cutaneous metastasis to the left anterior chest and left supraclavicular area was successfully treated with topical imiquimod. She experienced improvement in appearance and symptoms within several months of starting treatment, resulting in near resolution of her cutaneous metastasis. Imiquimod is currently approved for several cutaneous conditions and has the potential to treat cutaneous metastasis of breast cancer.

Indexed as

cutaneous metastasisImiquimodtherapytopical

Identifiers

PMID34249290
PMCPMC8239964
OpenAlexW3175222908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.