Evidence map›Paper›PMID 34249101›Full record

ArticleFrontiers in genetics2021

A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects.

Eszter Somogyi, Zsolt Csiszovszki, Levente Molnár, Orsolya Lőrincz, József Tóth, Sofie Pattijn, Jana Schockaert, Aurélie Mazy, István Miklós, Katalin Pántya and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  10. Safety and Activity of PolyPEPI1018 Combined with Maintenance Therapy in Metastatic Colorectal Cancer: an Open-Label, Multicenter, Phase Ib Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Eszter SomogyiTreos Bio Ltd., London, United Kingdom.
Zsolt CsiszovszkiTreos Bio Ltd., London, United Kingdom.
Levente MolnárTreos Bio Ltd., London, United Kingdom.
Orsolya LőrinczTreos Bio Ltd., London, United Kingdom.
József TóthTreos Bio Ltd., London, United Kingdom.
Sofie PattijnImmunXperts Société Anonyme, A Nexelis Group Company, Gosselies, Belgium.
Jana SchockaertImmunXperts Société Anonyme, A Nexelis Group Company, Gosselies, Belgium.
Aurélie MazyImmunXperts Société Anonyme, A Nexelis Group Company, Gosselies, Belgium.
István MiklósTreos Bio Ltd., London, United Kingdom.
Katalin PántyaTreos Bio Ltd., London, United Kingdom.
Péter PálesTreos Bio Ltd., London, United Kingdom.
Enikő R TőkeTreos Bio Ltd., London, United Kingdom.
Hungarian Research Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term immunity to coronaviruses likely stems from T cell activity. We present here a novel approach for the selection of immunoprevalent SARS-CoV-2-derived T cell epitopes using an

Indexed as

ethnic diversityglobal vaccineHLA-genotypein silico clinical trialSARS-CoV-2 immunity

Identifiers

PMID34249101
PMCPMC8261158
OpenAlexW3176171025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.