Evidence map›Paper›PMID 34249085›Full record

ArticleFrontiers in genetics2021

SNHG17 Serves as an Oncogenic lncRNA by Regulating the miR-361-3p/STC2 Axis in Rectal Cancer.

Fuda Huang, Hua Li, Zebang Qin, Anmin Wang, Ya Zhang, Junyu Guo, Mingwei Wei, Houji Guo, Jian Pu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Predictive Value ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target.Journal of experimental & clinical cancer research : CR · 2022
    Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fuda HuangProctology Department, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Hua LiProctology Department, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Zebang QinGraduate College, Youjiang Medical University for Nationalities, Baise, China.
Anmin WangGraduate College, Youjiang Medical University for Nationalities, Baise, China.
Ya ZhangGraduate College, Youjiang Medical University for Nationalities, Baise, China.
Junyu GuoProctology Department, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Mingwei WeiProctology Department, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Houji GuoProctology Department, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Jian PuDepartment of Hepatobiliary Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Affiliated Hospital of Youjiang Medical University for Nationalities · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNA (lncRNA) have been reported to be crucial regulators for carcinogenesis, including rectal cancer. This work aimed to explore the roles and associated mechanisms of small nucleolar RNA host gene 17 (SNHG17) in rectal cancer. A quantitative real-time polymerase chain reaction was performed to measure the expression level of SNHG17 in rectal cancer tissues and cells. Cell counting kit-8 (CCK-8) assay and flow cytometry assay were conducted to measure the biological roles of SNHG17 in rectal cancer. In addition, luciferase activity reporter assay, RNA immunoprecipitation (RIP) assay, and rescue experiments were conducted to explore the mechanisms of SNHG17 in rectal cancer. The upregulation status of SNHG17 was identified in rectal cancer tissues and cells. Functionally, knockdown the expression of SNHG17 inhibits rectal cancer cell proliferation

Indexed as

long non-coding RNAmiR-361-3prectal cancerSNHG17STC2

Identifiers

PMID34249085
PMCPMC8260683
OpenAlexW3174675948

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.