ArticleFrontiers in microbiology2021
Characterization of Supragingival Plaque and Oral Swab Microbiomes in Children With Severe Early Childhood Caries.
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Effects of silver diamine fluoride on oral bacteriome and mycobiome: a randomized clinical trial.BMC oral health · 2025Trial
- Oral microbiome diversity and composition before and after chemotherapy treatment in pediatric oncology patients.BMC oral health · 2025Trial
- Mapping the oral microbiome in children with oral diseases using next-generation sequencing: a systematic review.Journal of oral microbiology · 2026Review
- L-proline supplementation affects non-volatile flavour perception through oral microbiome metabolic pathways.NPJ science of food · 2025Article
- N-acyl homoserine lactone signaling modulates bacterial community associated with human dental plaque.NPJ biofilms and microbiomes · 2025Article
- Article
- A comparative study of microbial changes in dental plaque before and after single- and multiappointment treatments in patients with severe early childhood caries.BMC oral health · 2024Article
- Early life factors and oral microbial signatures define the risk of caries in a Swedish cohort of preschool children.Scientific reports · 2024Article
- Personalized Medicine in Oral Oncology: Imaging Methods and Biological Markers to Support Diagnosis of Oral Squamous Cell Carcinoma (OSCC): A Narrative Literature Review.Journal of personalized medicine · 2023Review
- Article
- Correlation between caries activity and salivary microbiota in preschool children.Frontiers in cellular and infection microbiology · 2023Article
- Can salivary microbiome become a biodetector for type-2 diabetes? Opinion for future implications and strategies.Frontiers in nutrition · 2023Article
- A toolbox of machine learning software to support microbiome analysis.Frontiers in microbiology · 2023Review
- Genetic variants in taste genes play a role in oral microbial composition and severe early childhood caries.iScience · 2022Article
- Determinants and Interactions of Oral Bacterial and Fungal Microbiota in Healthy Chinese Adults.Microbiology spectrum · 2022Article
- The Crosstalk Between Saliva Bacteria and Fungi in Early Childhood Caries.Frontiers in cellular and infection microbiology · 2022Article
- Susceptibility of Dental Caries Microcosm Biofilms to Photodynamic Therapy Mediated by Fotoenticine.Pharmaceutics · 2021Article
- Association of Bitter Taste Receptor T2R38 Polymorphisms, Oral Microbiota, and Rheumatoid Arthritis.Current issues in molecular biology · 2021Article
- Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human oral cavity harbors one of the most diverse microbial communities with different oral microenvironments allowing the colonization of unique microbial species. This study aimed to determine which of two commonly used sampling sites (dental plaque vs. oral swab) would provide a better prediction model for caries-free vs. severe early childhood caries (S-ECC) using next generation sequencing and machine learning (ML). In this cross-sectional study, a total of 80 children (40 S-ECC and 40 caries-free) < 72 months of age were recruited. Supragingival plaque and oral swab samples were used for the amplicon sequencing of the V4-16S rRNA and ITS1 rRNA genes. The results showed significant differences in alpha and beta diversity between dental plaque and oral swab bacterial and fungal microbiomes. Differential abundance analyses showed that, among others, the cariogenic species
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