ReviewFrontiers in microbiology2021
Structure, Application, and Biochemistry of Microbial Keratinases.
Review in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 78 citations in OpenAlex.
- First evidence of keratinolytic activity in Simplicillium aogashimaense isolated from wool-pellet-amended soil.Microbial cell factories · 2026Article
- Differentiating superficial fungal infection from eczema using a heated dynamic-headspace skin VOC sampler: a hypothesis.Frontiers in medicine · 2026Article
- Functional identification of a feather-degrading thermitase-like S8 serine protease fromFrontiers in microbiology · 2026Article
- Multi-omic profiling reveals the impact of keratinase kerZJ on mouse gut homeostasis.Journal of microbiology (Seoul, Korea) · 2025Article
- Proteolytic enzymes from Bacillus subtilis AB2 as antibiofilm adjuvants: Bioprocess optimization, mechanistic insights, and synergy with antibiotics.Journal of microbiology (Seoul, Korea) · 2025Article
- Feather Waste Biodegradation and Biostimulant Potential ofInternational journal of molecular sciences · 2025Article
- Keratinase and its diverse applications.3 Biotech · 2025Review
- Comparative analysis of pre-treatment strategies and bacterial strain efficiency for improvement of feather hydrolysis.Microbial cell factories · 2025Article
- Keratinous bioresources: their generation, microbial degradation, and value enhancement for biotechnological applications.World journal of microbiology & biotechnology · 2025Review
- An update on thermostable keratinases for protein engineering against feather pollutants.Applied microbiology and biotechnology · 2025Review
- Current Understanding of Feather Keratin and Keratinase and Their Applications in Biotechnology.Biochemistry research international · 2025Review
- Keratinous and corneous-based products towards circular bioeconomy: A research review.Environmental science and ecotechnology · 2024Review
- Alkaline keratinase fromHeliyon · 2024Article
- A Comparative Transcriptome Analysis Unveils the Mechanisms of Response in Feather Degradation byMicroorganisms · 2024Article
- Bacillus and Streptomyces spp. as hosts for production of industrially relevant enzymes.Applied microbiology and biotechnology · 2024Review
- Identification of molecular interactions of pesticides with keratinase for their potential to inhibit keratin biodegradation.In silico pharmacology · 2024Article
- Comprehensive insights into the mechanism of keratin degradation and exploitation of keratinase to enhance the bioaccessibility of soybean protein.Biotechnology for biofuels and bioproducts · 2023Article
- Structure prediction, docking studies and molecular cloning of novel Pichia kudriavzevii YK46 metalloprotease (MetPr) for improvement of feather waste biodegradation.Scientific reports · 2023Article
- Response surface methodology based optimization of keratinase fromSaudi journal of biological sciences · 2023Article
- Thermoactive metallo-keratinase fromHeliyon · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Keratinases belong to a class of proteases that are able to degrade keratins into amino acids. Microbial keratinases play important roles in turning keratin-containing wastes into value-added products by participating in the degradation of keratin. Keratin is found in human and animal hard tissues, and its complicated structures make it resistant to degradation by common proteases. Although breaking disulfide bonds are involved in keratin degradation, keratinase is responsible for the cleavage of peptides, making it attractive in pharmaceutical and feather industries. Keratinase can serve as an important tool to convert keratin-rich wastes such as feathers from poultry industry into diverse products applicable to many fields. Despite of some progress made in isolating keratinase-producing microorganisms, structural studies of keratinases, and biochemical characterization of these enzymes, effort is still required to expand the biotechnological application of keratinase in diverse fields by identifying more keratinases, understanding the mechanism of action and constructing more active enzymes through molecular biology and protein engineering. Herein, this review covers structures, applications, biochemistry of microbial keratinases, and strategies to improve its efficiency in keratin degradation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.