ArticleFrontiers in physiology2021
Investigating the Association of Wallerian Degeneration and Diaschisis After Ischemic Stroke With BOLD Cerebrovascular Reactivity.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Acupuncture for early Wallerian degeneration of bilateral brachium pontis: a case report.Journal of medical case reports · 2026Article
- Evaluating structural connectivity disruption after stroke: individual tractography or the use of a model-based approach?NeuroImage. Clinical · 2026Article
- Prevalence and Imaging Correlates of Cerebral Diaschisis After Ischemic Stroke: A Systematic Review and Meta-Analysis.Brain sciences · 2025Review
- Comparison of the Correlation Between Cerebral [Molecular imaging and biology · 2025Article
- Secondary thalamic dysfunction underlies abnormal large-scale neural dynamics in chronic stroke.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Effects of Cerebellar Non-Invasive Stimulation on Neurorehabilitation in Stroke Patients: An Updated Systematic Review.Biomedicines · 2024Review
- Reduced cerebral blood flow and cognitive dysfunction following isolated cerebellar infarction: two case reports.The Journal of international medical research · 2024Article
- Role of NADCellular and molecular neurobiology · 2023Review
- Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research.Neural plasticity · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWallerian degeneration and diaschisis are considered separate remote entities following ischemic stroke. They may, however, share common neurophysiological denominators, since they are both related to disruption of fiber tracts and brain atrophy over time. Therefore, with advanced multimodal neuroimaging, we investigate Wallerian degeneration and its association with diaschisis.
methodsIn order to determine different characteristics of Wallerian degeneration, we conducted examinations on seventeen patients with chronic unilateral ischemic stroke and persisting large vessel occlusion, conducting high-resolution anatomical magnetic resonance imaging (MRI) and blood oxygenation-level dependent cerebrovascular reactivity (BOLD-CVR) tests, as well as Diamox
resultsWallerian degeneration, found in 8 (47%) subjects, had a strong association with ipsilateral thalamic volume reduction (
conclusionWe show a strong association between Wallerian degeneration and ipsilateral thalamic diaschisis, indicating a structural pathophysiological relationship.
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