Evidence map›Paper›PMID 34248640›Full record

ArticleFrontiers in pharmacology2021

Structural Characterization and Immunomodulatory Activity of a Novel Polysaccharide From Lycopi Herba.

Wuxia Zhang, Yihua Hu, Jiaqi He, Dongdong Guo, Jinzhong Zhao, Peng Li

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Structure Identification ofMolecules (Basel, Switzerland) · 2024
    Article
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wuxia ZhangDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.
Yihua HuDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.
Jiaqi HeDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.
Dongdong GuoDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.
Jinzhong ZhaoDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.
Peng LiDepartment of Basic Science, Shanxi Agricultural University, Jinzhong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lycopi Herba has been broadly used as a traditional medicinal herb in Asia due to its ability to strengthen immunity. However, it is still obscure for its material basis and underlying mechanisms. Polysaccharide, as one of the most important components of most natural herbs, usually contributes to the immunomodulatory ability of herbs. Here, we aimed to detect polysaccharides from Lycopi Herba and examine their potential immunomodulatory activity. A novel polysaccharide (LHPW) was extracted from Lycopi Herba and purified by DEAE-52 cellulose chromatography and G-100 sephadex

Indexed as

immunological activityLycopi HerbaNF-κB pathwaypolysaccharidestructure

Identifiers

PMID34248640
PMCPMC8267152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.