Evidence map›Paper›PMID 34248493›Full record

ArticleFrontiers in neuroscience2021

Non-ketotic Hyperglycemia Chorea-Ballismus and Intracerebral Hemorrhage: A Case Report and Literature Review.

Mingming Dong, Jian-Yu E, Liyang Zhang, Weiyu Teng, Li Tian

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Diabetic striatopathy: A case report of haemichorea in an older adult woman with poorly controlled diabetes.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026
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  2. Review
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  11. Effect of acupuncture treatment on nonketotic hyperglycemic hemichorea-hemiballismus: a case report.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mingming DongDepartment of Neurology, The Fourth People's Hospital of Shenyang, Shenyang, China.
Jian-Yu EWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Liyang ZhangDepartment of Neurology, The Fourth People's Hospital of Shenyang, Shenyang, China.
Weiyu TengDepartment of Neurology, The First Hospital of China Medical University, Shenyang, China.
Li TianDepartment of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, China.
China Medical University · CNShenyang The Fourth Hospital of People · CNJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-ketotic hyperglycemia chorea-ballismus (NKH-CB) is a rare metabolical syndrome secondary to the hyperglycemic condition, which is characterized by a triad of acute or subacute hemichorea-hemiballismus, hyperglycemic state, and unique abnormalities limited to the striatum on neuroimaging. Several related case studies on this disorder have been reported previously, but NKH-CB had never been associated with intracerebral hemorrhage (ICH). Herein, we report an uncommon case of NKH-CB and ICH that occurred simultaneously in one patient, which provides a challenge for clinicians in making a correct diagnosis. An 88-year-old woman with a long-term history of poor-controlled type 2 diabetes mellitus and hypertension, who presented with a sudden-onset headache, restlessness, severe bilateral choreiform and ballistic movements, elevated levels of glucose and osmolality in the serum, an increased white blood cell count, and two-type hyperdense signs on CT imaging, was finally diagnosed with NKH-CB and ICH. Despite administrated active treatments, the patient's clinical status did not improve and ultimately passed away. This case is reported to remind clinicians to consider the possibility of NKH-CB when patients present sudden-onset choreiform and ballistic movements. It is also the first entity with two-type hyperdense signs on CT imaging simultaneously, which helps us distinguish NKH-CB from ICH more intuitively.

Indexed as

case reportdiabetic striatopathydifferential diagnosishyperdense signs on neuroimagingintracerebral hemorrhagemetabolical syndromenon-ketotic hyperglycemia chorea-ballismus

Identifiers

PMID34248493
PMCPMC8260933
OpenAlexW3177069034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.