ArticleFrontiers in neuroscience2021
Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis.
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In one paragraph
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- PTSD and epigenetic aging: a longitudinal meta-analysis.Psychological medicine · 2025Pooled it
- Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records.Molecular psychiatry · 2022Pooled it
- Mental Health and Physiological Biomarkers Under Legal Uncertainty: Evidence From Asylum Centers in Serbia.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- World Trade Center (WTC) Exposures and Cardiometabolic Risk Among WTC Health Program General Responders.American journal of public health · 2025Article
- Dog ownership may promote cardiometabolic health in U.S. military veterans.Scientific reports · 2023Article
- PTSD, Immune System, and Inflammation.Advances in experimental medicine and biology · 2023Article
- Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy.The American journal of psychiatry · 2022Article
- Methylation of the AIM2 gene: An epigenetic mediator of PTSD-related inflammation and neuropathology plasma biomarkers.Depression and anxiety · 2022Article
Corrections and comments
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Authors and funding
50 authors at 20 institutions in 5 countries.
Jennifer A SumnerDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
Adam X MaihoferDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Vasiliki MichopoulosDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Alex O RothbaumDepartment of Psychological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Lynn M AlmliNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Ole A AndreassenNORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Allison E Ashley-KochDuke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Dewleen G BakerDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Jean C BeckhamDurham VA Health Care System, Durham, NC, United States.
Bekh BradleyDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Gerome BreenGenetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.
Jonathan R I ColemanGenetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.
Anders M DaleDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Michelle F DennisDurham VA Health Care System, Durham, NC, United States.
Norah C FeenyDepartment of Psychological Sciences, Case Western Reserve University, Cleveland, OH, United States.
Carol E FranzDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Melanie E GarrettDuke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Charles F GillespieDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Guia GuffantiDepartment of Psychiatry, Harvard Medical School, Boston, MA, United States.
Michael A HauserDuke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Sian M J HemmingsDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Tanja JovanovicDepartment of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, Detroit, MI, United States.
Nathan A KimbrelDurham VA Health Care System, Durham, NC, United States.
William S KremenDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Bruce R LawfordSchool of Biomedical Sciences, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Mark W LogueNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, United States.
Adriana LoriDepartment of Gynecology and Obstetrics, Emory University, Atlanta, GA, United States.
Michael J LyonsDepartment of Psychological & Brain Sciences, Boston University, Boston, MA, United States.
Jessica Maples-KellerDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Matig R MavissakalianDepartment of Psychiatry, Case Western Reserve University, Cleveland, OH, United States.
Regina E McGlincheyGRECC/TRACTS, VA Boston Healthcare System, Boston, MA, United States.
Divya MehtaCenter for Genomics and Personalised Health, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Rebecca MellorGallipoli Medical Research Foundation, Greenslopes Private Hospital, Brisbane, QLD, Australia.
William MilbergGRECC/TRACTS, VA Boston Healthcare System, Boston, MA, United States.
Mark W MillerNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, United States.
Charles Phillip MorrisSchool of Biomedical Sciences, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Matthew S PanizzonDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Kerry J ResslerDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Victoria B RisbroughDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Barbara O RothbaumDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Peter Roy-ByrneDepartment of Psychology, University of Washington, Seattle, WA, United States.
Soraya SeedatDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Alicia K SmithDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Jennifer S StevensDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.
Leigh Luella van den HeuvelDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Joanne VoiseySchool of Biomedical Sciences, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Ross McD YoungSchool of Psychology and Counseling, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Lori A ZoellnerDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Caroline M NievergeltDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Erika J WolfNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, United States.
Emory University · USDuke University · USQueensland University of Technology · AUUniversity of California, San Diego · USCase Western Reserve University · USSouth African Medical Research Council · ZAVA Boston Healthcare System · USVA San Diego Healthcare System · USBoston University · USKing's College London · GBUniversity of Washington · USDurham VA Health Care System · USGreenslopes Private Hospital · AUHarvard University · USMcLean Hospital · USNational Center for PTSD · USNational Center on Birth Defects and Developmental Disabilities · USOslo University Hospital · NOUniversity of California, Los Angeles · USWayne State University · US
Funding
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1MThe VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4)R01AG050595 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELMAN, JEREMY A, FRANZ, CAROL ELAINE · 2015 to 2024
$28.0MThe VETSA Longitudinal MRI Twin Study of AgingR01AG022381 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2003 to 2019
$22.3MPsychiatric Genomics Consortium for PTSDR01MH106595 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KARESTAN C KOENEN, Caroline M Nievergelt · 2016 to 2026
$8.4MEmory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4MHostility, PTSD &Physical Health Risk Factors in WomenR01MH062482 · NIMH · DUKE UNIVERSITY · PI BECKHAM, JEAN C. · 2001 to 2013
$4.0MGenetic Predictors, Transcriptomic Biomarkers, & Neurobiological Signatures of Resilience to Alzheimer's DiseaseR01AG064955 · NIA · UPSTATE MEDICAL UNIVERSITY · PI FENNEMA-NOTESTINE, CHRISTINE, GLATT, STEPHEN J · 2019 to 2023
$3.8MPosttraumatic Stress and Cardiovascular Risk in Women: Tests of Biological MechanismsK01HL130650 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMNER, JENNIFER A · 2016 to 2020
$815kNeuroimaging Genetics of PTSDR21MH102834 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MILLER, MARK W · 2014 to 2015
$355kBLRD VA I01 BX004312CSRD VA I01 CX001276NCATS NIH HHS UL1 TR002378NHLBI NIH HHS K01 HL130650NIA NIH HHS R01 AG022381NIA NIH HHS R01 AG050595NIA NIH HHS R01 AG064955NICHD NIH HHS K12 HD085850NIMH NIH HHS R01 MH062482NIMH NIH HHS R01 MH106595NIMH NIH HHS R21 MH102834
Abstract
Growing research suggests that posttraumatic stress disorder (PTSD) may be a risk factor for poor cardiovascular health, and yet our understanding of who might be at greatest risk of adverse cardiovascular outcomes after trauma is limited. In this study, we conducted the first examination of the individual and synergistic contributions of PTSD symptoms and blood pressure genetics to continuous blood pressure levels. We harnessed the power of the Psychiatric Genomics Consortium-PTSD Physical Health Working Group and investigated these associations across 11 studies of 72,224 trauma-exposed individuals of European (
Indexed as
blood pressuregeneticsmeta-analysisposttraumatic stress disordertrans-ethnic
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.