Evidence map›Paper›PMID 34248422›Full record

ArticleJournal of the American Medical Directors Association2021

Incident Impaired Cognitive Function in Sarcopenic Obesity: Data From the National Health and Aging Trends Survey.

John A Batsis, Christian Haudenschild, Robert M Roth, Tyler L Gooding, Meredith N Roderka, Travis Masterson, John Brand, Matthew C Lohman, Todd A Mackenzie

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Medical Directors Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 6 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 6 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

John A BatsisGeisel School of Medicine at Dartmouth, Hanover, NH.
Christian HaudenschildGeisel School of Medicine at Dartmouth, Hanover, NH.
Robert M RothGeisel School of Medicine at Dartmouth, Hanover, NH.
Tyler L GoodingDepartment of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Meredith N RoderkaDepartment of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Travis MastersonGeisel School of Medicine at Dartmouth, Hanover, NH.
John BrandGeisel School of Medicine at Dartmouth, Hanover, NH.
Matthew C LohmanDepartment of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC.
Todd A MackenzieGeisel School of Medicine at Dartmouth, Hanover, NH.
Dartmouth College · USDartmouth–Hitchcock Medical Center · USUniversity of South Carolina · US

Funding

Mobile Health Obesity Wellness Intervention in Rural Older Adults_Res1K23AG051681 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BATSIS, JOHN A. · 2016 to 2022
$1.1M
NIA NIH HHS K23 AG051681
6 · The paper itself

Abstract

Objectives: The prevalence of obesity with sarcopenia is increasing in adults aged ≥65 years. This geriatric syndrome places individuals at risk for synergistic complications that leads to long-term functional decline. We ascertained the relationship between sarcopenic obesity and incident long-term impaired global cognitive function in a representative US population. Design: A longitudinal, secondary data set analysis using the National Health and Aging Trends Survey. Setting: Community-based older adults in the United States. Participants: Participants without baseline impaired cognitive function aged ≥65 years with grip strength and body mass index measures. Methods: Sarcopenia was defined using the Foundation for the National Institutes of Health Sarcopenia Project grip strength cut points (men <35.5 kg; women <20 kg), and obesity was defined using standard body mass index (BMI) categories. Impaired global cognition was identified as impairment in the Alzheimer's Disease-8 score or immediate/delayed recall, orientation, clock-draw test, date/person recall. Proportional hazard models ascertained the risk of impaired cognitive function over 8 years (referent = neither obesity or sarcopenia). Results: Of the 5822 participants (55.7% women), median age category was 75 to 80, and mean grip strength and BMI were 26.4 kg and 27.5 kg/m Conclusions: Both sarcopenia and sarcopenic obesity are associated with an increased long-term risk of impaired cognitive function in older adults.

Indexed as

SarcopeniaAgedAgingBody CompositionBody Mass IndexCognitionCross-Sectional StudiesFemaleHumansMaleObesitycognitionobesitySarcopenia

Identifiers

PMID34248422
PMCPMC8269419
OpenAlexW3094496244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.