Evidence map›Paper›PMID 34248417›Full record

ReviewThe obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists2021

Options for acquiring motherhood in absolute uterine factor infertility; adoption, surrogacy and uterine transplantation.

Benjamin P Jones, Niccole Ranaei-Zamani, Saaliha Vali, Nicola Williams, Srdjan Saso, Meen-Yau Thum, Maya Al-Memar, Nuala Dixon, Gillian Rose, Giuliano Testa and 4 more

Open access · hybridAbstract readReview
In one paragraph

Review in The obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  7. Comparison ofInternational journal of fertility & sterility · 2025
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  8. Mayer-Rokitansky-Kuster-Hauser syndrome.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
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  19. Options for acquiring motherhood in absolute uterine factor infertility; adoption, surrogacy and uterine transplantation.The obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Benjamin P JonesClinical Research Fellow Department of Surgery and Cancer Imperial College London Du Cane Road London W12 0NN UK.ORCID https://orcid.org/0000-0002-0391-0443
Niccole Ranaei-ZamaniClinical Research Fellow Department of Surgery and Cancer Imperial College London Du Cane Road London W12 0NN UK.
Saaliha ValiSpecialty Trainee in Obstetrics and Gynaecology Queen Charlotte's & Chelsea Hospital Imperial College NHS Trust London W12 OHS UK.
Nicola WilliamsResearch Associate in Ethics Department of Politics, Philosophy and Religion Lancaster University Lancaster LA14YQ UK.
Srdjan SasoGynaecology Oncolology Subspecialty Trainee Hammersmith Hospital Imperial College NHS Trust London W12 OHS UK.
Meen-Yau ThumFertility Specialist The Lister Fertility Clinic London SW1W 8RH UK.
Maya Al-MemarSpecialty Trainee in Obstetrics and Gynaecology Queen Charlotte's & Chelsea Hospital Imperial College NHS Trust London W12 OHS UK.
Nuala DixonClinical Nurse Specialist Queen Charlotte's & Chelsea Hospital Imperial College NHS Trust London W12 OHS UK.
Gillian RoseConsultant Gynaecologist Queen Charlotte's & Chelsea Hospital Imperial College NHS Trust London W12 OHS UK.
Giuliano TestaTransplant Surgeon Baylor University Medical Center Dallas Texas 75246-2088 USA.
Liza JohannessonGynaecology Oncology Surgeon and Medical Director of Uterus Transplant Baylor University Medical Center Dallas Texas 75246-2088 USA.ORCID https://orcid.org/0000-0001-8572-3811
Joseph YazbekConsultant Gynaecologist Hammersmith Hospital Imperial College NHS Trust London W12 OHS UK.
Stephen WilkinsonProfessor of Bioethics Department of Politics, Philosophy and Religion Lancaster University Lancaster LA14YQ UK.
J Richard SmithConsultant Gynaecologist Hammersmith Hospital Imperial College NHS Trust London W12 OHS UK.
Queen Charlotte's and Chelsea Hospital · GBHammersmith Hospital · GBBaylor University Medical Center · USImperial College London · GBLancaster University · GBLister Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

key contentFollowing the diagnosis of absolute uterine factor infertility (AUFI), women may experience considerable psychological harm as a result of a loss of reproductive function and the realisation of permanent and irreversible infertility.Adoption enables women with AUFI, and their partners, to experience social and legal parenthood, also often providing benefits for the adopted child.Surrogacy offers the opportunity to have genetically related offspring. Outcomes are generally positive in both surrogates and the children born as a result.Uterine transplantation is the only option to restore reproductive anatomy and functionality. While associated with considerable risk, it allows the experience of gestation and the achievement of biological, social and legal parenthood. LEARNING

objectivesTo gain an understanding of the routes to parenthood available for women with AUFI experiencing involuntary childlessness, such as adoption, surrogacy and, most recently, uterine transplantationTo consider a suggested management plan to facilitate counselling in women with AUFI who experience involuntary childlessness. ETHICAL ISSUES: In the UK, while the number of children requiring adoption continues to increase, the number being adopted from care is decreasing.Some cultures may hold ethical or religious beliefs that surrogacy is unacceptable, and its legal position in many jurisdictions is problematic.Restrictive selection criteria and high costs may limit future availability of uterine transplantation.

Indexed as

adoptioninfertilitysurrogacytransplantationuterus

Identifiers

PMID34248417
PMCPMC8252631
OpenAlexW3132408220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.