ArticleHelminthologia2021
Physiological, Immunological and Genetic Factors in the Resistance and Susceptibility to Gastrointestinal Nematodes of Sheep in the Peripartum Period: A Review.
Article in Helminthologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Prevalence and Diversity of Gastrointestinal Nematodes in Small Ruminants in Iran: a Systematic Review and Meta-analysis.Acta parasitologica · 2025Pooled it
- Cross-sectional study of gastrointestinal helminthosis in goats from three ecosystems in Peru: Prevalence and associated factors.Parasitology research · 2025Article
- Classification of productive hair ewes using hematocrit as a marker of resistance to gastrointestinal nematodes.Open veterinary journal · 2025Article
- Using an Aqueous Suspension ofPathogens (Basel, Switzerland) · 2025Article
- Prevalence of Coccidia and Other Intestinal Parasites in Indigenous Sheep (Veterinary medicine international · 2025Article
- Effect of pomegranate (Frontiers in veterinary science · 2024Article
- Effect of age, sex, and county on postmortem findings in goats and sheep in Tennessee (USA), 2017-2021.PloS one · 2024Article
- Optimum timing for assessing phenotypic resistance against gastrointestinal nematodes in Pelibuey ewes.Helminthologia · 2023Article
- Oxidative Stress and High-Mobility Group Box 1 Assay in Dogs with Gastrointestinal Parasites.Antioxidants (Basel, Switzerland) · 2022Article
- Protein Supplementation as a Nutritional Strategy to Reduce Gastrointestinal Nematodiasis in Periparturient and Lactating Pelibuey Ewes in a Tropical Environment.Pathogens (Basel, Switzerland) · 2022Article
- Comprehensive diagnosis of parasites in sheep kept under different zootechnical management in a region temperate in Mexico.Veterinary research communications · 2022Article
- Variants Within GenesFrontiers in genetics · 2022Article
- Prevalence, species composition, and associated risk factors of small ruminant gastrointestinal nematodes in South Omo zone, South-western Ethiopia.Journal of advanced veterinary and animal research · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasitic diseases of sheep involving gastrointestinal nematodes (GIN) are one of the main problems that affect fl ock productivity, especially during the peripartum period. Around lambing, the ewes are immunosuppressed and the nematode faecal egg count (FEC) increases at four weeks before lambing, reaching a peak between the fourth and sixth week postpartum and subsequently decreasing towards weaning. Prolactin has been credited with a suppressive effect on immune system, along with other hormones that intervene in metabolism, such as leptin, which has an important role in the activation of other hormones. Cortisol has also been included; this is stimulated by any stressful event and inhibits the proliferation of T-cells and alters the function of immunoglobulins. Another related hormone is pepsinogen, which is considered a marker of the integrity of the abomasum mucosa, as well as the albumin concentration that increases in the presence of a GIN infection. The humoral and cellular immune response, as well as inflammatory reactions, are the main mechanisms of action against GIN. Lymphocytes direct the effector mechanisms in a Th2 cell response, including interleukins (IL-4, IL-5, IL-9, IL-10) and transforming growth factor beta (TGF-β) together with immunoglobulins (IgA, IgG, IgM and IgE), which prevent the invasion of pathogens. Eosinophils with a cytotoxic effect are indicators of a parasitic infection, with importance in the immune protection of infected individuals. The genetic selection of resistant individuals measured by FEC is dependent on the heritability (h
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