Evidence map›Paper›PMID 34248138›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2021

Characteristics and Related Factors of High-Risk Human Papillomavirus Infection in Pregnant Women.

Yingying Chen, Jie Dong, Boliang Chu, Xiaoxing Zhang, Xiaofang Ru, Yun Chen, Yunyan Chen, Xiaodong Cheng

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yingying ChenDepartment of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).
Jie DongDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Boliang ChuDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Xiaoxing ZhangDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Xiaofang RuDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Yun ChenDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Yunyan ChenDepartment of Obstetrics and Gynecology, Huzhou Maternal & Child Health Care Hospital, Huzhou, Zhejiang, China (mainland).
Xiaodong ChengDepartment of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).
Huzhou Women and Children's Hospital · CNWomen's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Cervical cancer is a risk for women worldwide. The aim of this study was to examine the occurrence of high-risk human papillomavirus (HR-HPV) infection and its related factors in pregnant women and provide a scientific basis for the targeted prevention and treatment of cervical cancer in pregnant women. MATERIAL AND METHODS A total of 1774 pregnant women were included, and 1774 non-pregnant women were selected as controls. Cervical exfoliated cells were collected from all women for HR-HPV (AptimaE6, E7mRNA) and ThinPrep cytologic testing, and the vaginal discharge of all pregnant women was tested for pH level and routine pathogenic microorganisms. RESULTS The HPV-16-positive and HPV-16/18/45-positive rates in pregnant women were higher than those of non-pregnant women (P<0.05). There was a statistically significant difference in HR-HPV-positive rate, HPV-16-positive rate, and non-HPV-16/18/45-positive rate among pregnant women of different ages (P<0.05). There was a statistically significant difference in HR-HPV-positive rate and non-HPV-16/18/45-positive rate in the first, second, and third trimester (P<0.05). The HR-HPV-positive rate, HPV-16-positive rate, HPV-18/45-positive rate, and non-HPV-16/18/45-positive rate of pregnant women with concurrent infection were higher than those in women without concurrent infection (P<0.05). The HR-HPV-positive and HPV-16/18/45-positive rates in pregnant women were associated with cytologic examination results (P<0.05). CONCLUSIONS The overall infection rates of HR-HPV-16 and HR-HPV-18/45 in pregnant women were higher than those in non-pregnant women. The gestation period was found to be a susceptible period for infection with HR-HPV, and we recommend the implementation of cervical cancer screening based on HR-HPV testing in pregnant women.

Indexed as

AdultEarly Detection of CancerFemaleHuman papillomavirus 16HumansMiddle AgedPapillomavirus InfectionsPregnancyPregnant PeopleUterine Cervical Neoplasms

Identifiers

PMID34248138
PMCPMC8284082
OpenAlexW3151261695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.