Evidence map›Paper›PMID 34247609›Full record

ArticleBMC public health2021

Application of a novel hybrid algorithm of Bayesian network in the study of hyperlipidemia related factors: a cross-sectional study.

Xuchun Wang, Jinhua Pan, Zeping Ren, Mengmeng Zhai, Zhuang Zhang, Hao Ren, Weimei Song, Yuling He, Chenglian Li, Xiaojuan Yang and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Xuchun Wang *Department of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Jinhua Pan *Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai, 200032, China.
Zeping Ren *Shanxi Centre for Disease Control and Prevention, Taiyuan, 030012, Shanxi, China.
Mengmeng ZhaiDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Zhuang ZhangDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Hao RenDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Weimei SongDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Yuling HeShanxi Centre for Disease Control and Prevention, Taiyuan, 030012, Shanxi, China.
Chenglian LiShanxi Centre for Disease Control and Prevention, Taiyuan, 030012, Shanxi, China.
Xiaojuan YangShanxi Centre for Disease Control and Prevention, Taiyuan, 030012, Shanxi, China.
Meichen LiDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Dichen QuanDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Limin ChenShanxi Provincial People's Hospital, Taiyuan city, Shanxi Province, China. sxchenlimin@163.com.
Lixia QiuDepartment of Health Statistics, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. qlx_1126@163.com.
Shanxi Medical University · CNFudan University · CN

Funding

National Natural Science Foundation of China Project 81973155
6 · The paper itself

Abstract

backgroundThis article aims to understand the prevalence of hyperlipidemia and its related factors in Shanxi Province. On the basis of multivariate Logistic regression analysis to find out the influencing factors closely related to hyperlipidemia, the complex network connection between various variables was presented through Bayesian networks(BNs).

methodsLogistic regression was used to screen for hyperlipidemia-related variables, and then the complex network connection between various variables was presented through BNs. Since some drawbacks stand out in the Max-Min Hill-Climbing (MMHC) hybrid algorithm, extra hybrid algorithms are proposed to construct the BN structure: MMPC-Tabu, Fast.iamb-Tabu and Inter.iamb-Tabu. To assess their performance, we made a comparison between these three hybrid algorithms with the widely used MMHC hybrid algorithm on randomly generated datasets. Afterwards, the optimized BN was determined to explore to study related factors for hyperlipidemia. We also make a comparison between the BN model with logistic regression model.

resultsThe BN constructed by Inter.iamb-Tabu hybrid algorithm had the best fitting degree to the benchmark networks, and was used to construct the BN model of hyperlipidemia. Multivariate logistic regression analysis suggested that gender, smoking, central obesity, daily average salt intake, daily average oil intake, diabetes mellitus, hypertension and physical activity were associated with hyperlipidemia. BNs model of hyperlipidemia further showed that gender, BMI, and physical activity were directly related to the occurrence of hyperlipidemia, hyperlipidemia was directly related to the occurrence of diabetes mellitus and hypertension; the average daily salt intake, daily average oil consumption, smoking, and central obesity were indirectly related to hyperlipidemia.

conclusionsThe BN of hyperlipidemia constructed by the Inter.iamb-Tabu hybrid algorithm is more reasonable, and allows for the overall linking effect between factors and diseases, revealing the direct and indirect factors associated with hyperlipidemia and correlation between related variables, which can provide a new approach to the study of chronic diseases and their associated factors.

Indexed as

HyperlipidemiasAlgorithmsBayes TheoremCross-Sectional StudiesHumansLogistic ModelsBayesian networkHybrid algorithmHyperlipidemiaInter. Iamb-Tabu

Identifiers

PMID34247609
PMCPMC8273956
OpenAlexW3181049569

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.