Evidence map›Paper›PMID 34247512›Full record

Trial reportHypertension (Dallas, Tex. : 1979)2021

Effects of Experimental Sleep Restriction on Ambulatory and Sleep Blood Pressure in Healthy Young Adults: A Randomized Crossover Study.

Naima Covassin, Jan Bukartyk, Prachi Singh, Andrew D Calvin, Erik K St Louis, Virend K Somers

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Heart rate and vascular responses to spontaneous arousals following experimental sleep restriction.American journal of physiology. Heart and circulatory physiology · 2026
    Article
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  7. Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Naima CovassinDepartment of Cardiovascular Medicine (N.C., J.B., P.S., V.K.S.), Mayo Clinic, Rochester, MN.
Jan BukartykDepartment of Cardiovascular Medicine (N.C., J.B., P.S., V.K.S.), Mayo Clinic, Rochester, MN.
Prachi SinghDepartment of Cardiovascular Medicine (N.C., J.B., P.S., V.K.S.), Mayo Clinic, Rochester, MN.
Andrew D CalvinDepartment of Cardiovascular Medicine, Mayo Clinic Health System, Eau Claire, WI (A.D.C.).
Erik K St LouisCenter for Sleep Medicine, Department of Neurology (E.K.S.L.), Mayo Clinic, Rochester, MN.
Virend K SomersDepartment of Cardiovascular Medicine (N.C., J.B., P.S., V.K.S.), Mayo Clinic, Rochester, MN.
Mayo Clinic · USMayo Clinic Health System · USPennington Biomedical Research Center · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Disease Mechanisms in Sleep ApneaR01HL065176 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 1999 to 2021
$5.8M
Sleep Enhancement to Decrease Blood Pressure: A Randomized, Controlled TrialR01HL134808 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2017 to 2021
$3.9M
Sleep Apnea and Hypertrophic Cardiomyopathy - Implications for Arrhythmia and Sudden DeathR01HL134885 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2017 to 2020
$3.0M
Sleep Restriction and Augmented Vascular Risk in PrehypertensionR01HL114676 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2012 to 2016
$2.4M
NCATS NIH HHS UL1 TR002377NHLBI NIH HHS R01 HL065176NHLBI NIH HHS R01 HL114676NHLBI NIH HHS R01 HL134808NHLBI NIH HHS R01 HL134885NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AdolescentAdultBiomarkersBlood PressureBlood Pressure Monitoring, AmbulatoryCross-Over StudiesFemaleHumansMalePolysomnographySleepSleep DeprivationYoung AdultBiomarkersbiomarkersblood pressurecardiovascular diseasessexsleep

Identifiers

PMID34247512
PMCPMC8363516
OpenAlexW3182406493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.