ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
Epigenetic mechanisms in sex determination and in the evolutionary transitions between sexual systems.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Multivariate Models of Animal Sex: Breaking Binaries Leads to a Better Understanding of Ecology and Evolution.Integrative and comparative biology · 2023Pooled it
- Allele-specific methylation ofScience advances · 2026Article
- Sex Determination in Sponges.Molecular reproduction and development · 2026Review
- An Epigenetic Clock for Accurate Age Prediction in Atlantic Cod Populations for Improved Fisheries Management.Molecular ecology resources · 2026Article
- Hermaphrodite, Gonochorist, and More: Navigating the Complexities of Sex-Related Language in Biology.Integrative and comparative biology · 2026Review
- Reversibility of sex changes in the plant kingdom: more important than we thought?Biological reviews of the Cambridge Philosophical Society · 2025Review
- Oysters in transition: hermaphrodite oysters display unique DNA methylation patterns in gill tissue.BMC genomics · 2025Article
- Sex-biased gene expression precedes sexual dimorphism in the agonadal annelid Platynereis dumerilii.Development (Cambridge, England) · 2025Article
- Chromosome-level genome assembly and methylome profile yield insights for the conservation of endangered loggerhead sea turtles.GigaScience · 2025Article
- Identification of a candidate sex determination region and sex-specific molecular markers based on whole-genome re‑sequencing in the sea star Asterias amurensis.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024Article
- Methylome profile of medaka eggs and sperm.Epigenetics · 2024Article
- Sex-biased gene expression precedes sexual dimorphism in the agonadal annelidbioRxiv : the preprint server for biology · 2024Article
- Fish reproduction in a warming world: vulnerable points in hormone regulation from sex determination to spawning.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Understanding the genetic sex-determining mechanism in Hyla eximia treefrog inferred from H-Y antigen.PloS one · 2024Article
- Sex-specific DNA methylation and transcription ofEpigenetics · 2023Article
- Review
- Sex-specific DNA methylation: impact on human health and development.Molecular genetics and genomics : MGG · 2022Review
- Switches, stability and reversals in the evolutionary history of sexual systems in fish.Nature communications · 2022Article
- Identification of sex determination locus in sea cucumber Apostichopus japonicus using genome-wide association study.BMC genomics · 2022Article
- Expanding the classical paradigm: what we have learnt from vertebrates about sex chromosome evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hypothesis that epigenetic mechanisms of gene expression regulation have two main roles in vertebrate sex is presented. First, and within a given generation, by contributing to the acquisition and maintenance of (i) the male
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.