Evidence map›Paper›PMID 34247257›Full record

ArticleLangenbeck's archives of surgery2021

Does delaying curative surgery for colorectal cancer influence long-term disease-free survival? A cohort study.

Stephanie Garcia-Botello, J Martín-Arevalo, C Cozar-Lozano, A Benitez-Riesco, D Moro-Valdezate, V Pla-Martí, A Espí-Macías

Open access · hybridAbstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. [Influencing Factors of Adherence to Exercise Prehabilitation in Older Patients With Colorectal Cancer: A Qualitative Study].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephanie Garcia-BotelloColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain. stephanie.garcia@uv.es.ORCID http://orcid.org/0000-0001-6921-4902
J Martín-ArevaloColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
C Cozar-LozanoColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
A Benitez-RiescoColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
D Moro-ValdezateColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
V Pla-MartíColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
A Espí-MacíasColorectal Surgery Unit, Biomedical Research Institute INCLIVA, Hospital Clinico Universitario, Valencia, Spain.
Universitat de València · ESINCLIVA Health Research Institute · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical wait list time is a major problem in many health-care systems and its influence on survival is unclear. The aim of this study is to assess the impact of wait list time on long-term disease-free survival in patients scheduled for colorectal cancer resection. MATERIALS AND

methodsA prospective study was carried out in patients with colorectal cancer scheduled for surgery at a tertiary care center. Wait list time was defined as the time from completion of diagnostic workup to definitive surgery and divided into 2-week intervals from 0 to 6 weeks. The outcome variables were 2-year and 5-year disease-free survival.

resultsA total of 602 patients, 364 (60.5%) male, median age 73 years (range = 71) were defined. The median wait list time was 28 days (range = 99). Two and 5-year disease-free survival rates were 521 (86.5%) and 500 (83.1%) respectively. There were no differences in 2-year or 5-year disease-free survival for the whole cohort or by tumor stage between wait list time intervals except for AJCC stage II tumors which showed a higher 5-year disease-free survival for the 2-4 and 4-6-week wait list time interval (p = 0.021).

conclusionsTime from diagnosis to definitive surgery up to 6 weeks is not associated with a decrease in 2-year or 5-year disease-free survival (DFS) in AJCC stage I through III colorectal cancer patients. These are important findings in the light of the COVID-19 pandemic and offer a window of opportunity for preoperative optimization and prehabilitation.

Indexed as

Colorectal NeoplasmsCOVID-19AgedCohort StudiesDisease-Free SurvivalHumansMalePandemicsProspective StudiesRetrospective StudiesSARS-CoV-2Colorectal cancerSurvivalWait list time

Identifiers

PMID34247257
PMCPMC8272683
OpenAlexW3180101353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.