Evidence map›Paper›PMID 34247188›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2022

Cerebral saturation reflects anterior cerebral artery flow parameters by Doppler ultrasound in the extremely premature newborn.

Gabriel Altit, Shazia Bhombal, Valerie Y Chock

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gabriel AltitDepartment of Pediatrics, Division of Neonatology; Montreal Children's Hospital, McGill University Health Center, Montreal, Canada. Gabriel.altit@mail.mcgill.ca.ORCID http://orcid.org/0000-0001-5141-0964
Shazia BhombalDivision of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford, Stanford, Canada.ORCID http://orcid.org/0000-0003-4581-246X
Valerie Y ChockDivision of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford, Stanford, Canada.
Montreal Children's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNear-infrared spectroscopy measures cerebral saturation (Csat), although correlation with cerebral blood flow remains unclear in premature newborns at risk for intraventricular hemorrhage (IVH).

objectivesCompare Doppler markers of anterior cerebral artery (ACA) flow with Csat obtained during head ultrasound (HUS).

methodNewborns <29 weeks (2013-2017) underwent Csat monitoring with clinical acquisition of HUS. ACA Doppler markers were measured (with and without pressure) and Resistive Index (RI) was calculated. Mixed effects models evaluated the association between Csat and Doppler markers.

results98 neonates with 175 Csat-HUS observations were analyzed. Age at birth was 26.2 ± 1.5 weeks, with post-menstrual age of 26.9 ± 1.7 weeks at HUS. Csat was associated with RI without pressure (p = 0.045), RI with pressure (p = 0.019), and peak systolic velocity with pressure (p = 0.036). Severe IVH (n = 27 [15%]) was associated with lower Csat (60 ± 11% vs 68 ± 9%, p = 0.01).

conclusionCsat was associated with ACA Doppler measurements in extremely premature neonates.

Indexed as

Anterior Cerebral ArteryCerebrovascular CirculationBlood Flow VelocityCerebral HemorrhageHumansInfantInfant, NewbornUltrasonographyUltrasonography, Doppler

Identifiers

PMID34247188
OpenAlexW3178446383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.