ArticleCerebrovascular diseases (Basel, Switzerland)2021
Delayed Stroke Treatment during COVID-19 Pandemic in China.
Article in Cerebrovascular diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses.Globalization and health · 2022Pooled it
- Efficacy and safety of recanalization therapy for acute ischemic stroke with COVID-19: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Quality of care for acute ischemic stroke in China during the COVID-19 pandemic: a retrospective study using a National database.BMC public health · 2025Observational
- Observational
- The impacts of mask-wearing regulations on stroke morbidity and mortality: a population-based retrospective cohort study in China.BMC public health · 2024Article
- Stroke nurse-led intravenous thrombolytic therapy strategy for ischemic stroke based on timeline process: A quality improvement program from China.International journal of nursing sciences · 2024Article
- Analysis of onset-to-door time and its influencing factors in Chinese patients with acute ischemic stroke during the 2020 COVID-19 epidemic: a preliminary, prospective, multicenter study.BMC health services research · 2024Article
- The Scabbard of Excalibur: An Allegory on the Role of an Efficient and Effective Healthcare System under Universal Health Coverage during the Pandemic Response.Healthcare (Basel, Switzerland) · 2024Article
- Healthcare-Seeking Delays in Acute Ischemic Stroke Patients: The Influence of Gender, Immigrant Status, and Educational Background.Risk management and healthcare policy · 2024Article
- Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.Frontiers in neurology · 2024Article
- Impact of an Emergency Department Isolation Policy for Patients With Suspected COVID-19 on Door-to-Electrocardiography Time and Clinical Outcomes in Patients With Acute Myocardial Infarction.Journal of Korean medical science · 2023Article
- Epidemiology, pathogenesis, and management of Coronavirus disease 2019-associated stroke.Frontiers of medicine · 2023Review
- Cardiovascular Health Care Implications of the COVID-19 pandemic.Heart failure clinics · 2023Review
- Coronavirus disease 2019 and acute cerebrovascular events: a comprehensive overview.Frontiers in neurology · 2023Review
- Temporal Trends in Patients with Peripheral Artery Disease Influenced by COVID-19 Pandemic.Journal of clinical medicine · 2022Article
- Cardiovascular Health Care Implications of the COVID-19 pandemic.Cardiology clinics · 2022Review
- Severe stroke in patients admitted to intensive care unit after COVID-19 infection: Pictorial essay of a case series.Brain hemorrhages · 2022Article
- The impact of COVID-19 pandemic on treatment delay and short-term neurological functional prognosis for acute ischemic stroke during the lockdown period.Frontiers in neurology · 2022Article
- The Impact of COVID-19 Pandemic on Ischemic Stroke Patients in a Comprehensive Hospital.Risk management and healthcare policy · 2022Article
- Delayed Stroke Treatment during COVID-19 Pandemic in China.Cerebrovascular diseases (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSocial distance, quarantine, pathogen testing, and other preventive strategies implemented during CO-VID-19 pandemic may negatively influence the management of acute ischemic stroke (AIS).
objectiveThe current study aimed to evaluate the impacts of COVID-19 pandemic on treatment delay of AIS in China.
methodsThis study included patients with AIS admitted in 2 hospitals in Jiangsu, China. Patients admitted before and after the COVID-19 pandemic outbreak (January 31, 2020, as officially announced by the Chinese government) were screened to collect sociodemographic data, medical history information, and symptom onset status from clinical medical records and compared for pre- (measured as onset-to-door time [ODT]) and posthospital delay (measured as door-to-needle time [DNT]). The influencing factors for delayed treatment (indicated as onset-to-needle time >4.5 h) were analyzed with multivariate logistic regression analysis.
resultsA total of 252 patients were included, of which 153 (60.7%) were enrolled before and 99 (39.3%) after the COVID-19 pandemic. ODT increased from 202 min (interquartile range [IQR] 65-492) before to 317 min (IQR 75-790) after the COVID-19 pandemic (p = 0.001). DNT increased from 50 min (IQR 40-75) before to 65 min (IQR 48-84) after the COVID-19 pandemic (p = 0.048). The proportion of patients with intravenous thrombolysis in those with AIS was decreased significantly after the pandemic (15.4% vs. 20.1%; p = 0.030). Multivariate logistic regression analysis indicated that patients after COVID-19 pandemic, lower educational level, rural residency, mild symptoms, small artery occlusion, and transported by other means than ambulance were associated with delayed treatment.
conclusionsCOVID-19 pandemic has remarkable impacts on the management of AIS. Both pre- and posthospital delays were prolonged significantly, and proportion of patients arrived within the 4.5-h time window for intravenous thrombolysis treatment was decreased. Given that anti-COVID-19 measures are becoming medical routines, efforts are warranted to shorten the delay so that the outcomes of stroke could be improved.
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