Evidence map›Paper›PMID 34247064›Full record

ArticleCancer epidemiology2021

Sexual identity differences in biomarkers of tobacco exposure among women in a national sample.

Rebecca J Evans-Polce, Danielle M Smith, Philip Veliz, Carol J Boyd, Sean Esteban McCabe

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Rebecca J Evans-PolceCenter for the Study of Drugs, Alcohol, Smoking and Health Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA. Electronic address: bjevans@umich.edu.
Danielle M SmithDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Philip VelizCenter for the Study of Drugs, Alcohol, Smoking and Health Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Carol J BoydCenter for the Study of Drugs, Alcohol, Smoking and Health Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA; Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Sean Esteban McCabeCenter for the Study of Drugs, Alcohol, Smoking and Health Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Center for Sexuality and Health Disparities, School of Nursing, University of Michigan, Ann Arbor, MI, USA.
Institute for Women's Policy Research · USUniversity of Michigan · USRoswell Park Comprehensive Cancer Center · US

Funding

WNY Center for Research on Flavored Tobacco Products (CRoFT)U54CA228110 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI LI, DONGMEI · 2018 to 2022
$19.8M
Discrimination, Stress and Substance Use Disorder among Sexual Minority Adults: A Secondary Analysis of NESARC-IIIR01DA043696 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2017 to 2019
$1.1M
Health, Stress, and Tobacco Use Disparities among Sexual Minority PopulationsR01CA212517 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2017 to 2019
$721k
Prospective Examination of E-Cigarette Use, Tobacco Use Disorder and Health Consequences by U.S. YouthR01DA044157 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2018 to 2020
$702k
E-Cigarette Use and Longitudinal Changes in Cigarette Smoking and HealthR01CA203809 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2016 to 2018
$652k
Tobacco Use Trajectories And Disparities Among Sexual Minorities In U.S Adolescents And AdultsR21DA051388 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EVANS-POLCE, REBECCA J. · 2020 to 2021
$429k
NCI NIH HHS R01 CA203809NCI NIH HHS R01 CA212517NCI NIH HHS U54 CA228110NIDA NIH HHS R01 DA043696NIDA NIH HHS R01 DA044157NIDA NIH HHS R21 DA051388
6 · The paper itself

Abstract

backgroundSexual minority women are consistently at increased risk for tobacco use compared to heterosexual women. Neither biomarkers of nicotine exposure nor biomarkers of tobacco toxicant exposure have been examined by sexual identity.

methodsThis study used interview and biomarker data from women in the biomarker core sample of Wave 1 of the Population Assessment of Tobacco and Health (PATH) study (2013-2014; n = 4930). We examined associations of sexual identity with nicotine exposure (measured with urinary cotinine and TNE-2) and with tobacco-specific nitrosamines (measured with urinary NNAL). Multivariable regression modeling was used to examine these associations among the full biomarker core sample, among past 30-day tobacco users, and among exclusive established cigarette users before and after controlling for tobacco use quantity and intensity.

resultsIn the full biomarker sample of women, prior to adjusting for tobacco use quantity and intensity, bisexual women had significantly higher cotinine, TNE-2, and NNAL levels compared to heterosexual women. Among exclusive established cigarette users, gay/lesbian women had significantly higher NNAL compared to heterosexual women prior to adjusting for tobacco quantity and intensity. No differences by sexual identity were found after adjusting for tobacco use quantity and intensity.

conclusionsThis is the first study to demonstrate differences in biological markers of tobacco exposure by sexual identity among women in the U.S. This has important public health implications as greater exposure to both nicotine and to tobacco-specific nitrosamines are strongly linked to cancer risk.

Indexed as

Tobacco ProductsBiomarkersCotinineHumansNicotineBiomarkersCotinineNicotineBiomarkers of exposureHealth disparitiesSexual identityTobacco useWomen’s health

Identifiers

PMID34247064
PMCPMC8455424
OpenAlexW3181341848

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.