Evidence map›Paper›PMID 34246855›Full record

ArticleSexual medicine2021

The Prevalence and Predictors of Penile Pain in Men with Peyronie's Disease.

Jose M Flores, Carolyn A Salter, Bruno Nascimento, Jean-Etienne Terrier, Hisanori Taniguchi, Helen L Bernie, Eduardo Miranda, Lawrence Jenkins, Elizabeth Schofield, John P Mulhall

Open access · goldAbstract read
In one paragraph

Article in Sexual medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Cryoablation of the penile nerves for chronic penile pain.International journal of impotence research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jose M FloresSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Carolyn A SalterSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Bruno NascimentoSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Jean-Etienne TerrierSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Hisanori TaniguchiSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Helen L BernieSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Eduardo MirandaSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Lawrence JenkinsSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Elizabeth SchofieldDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.
John P MulhallSexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: mulhalj1@mskcc.org.
Memorial Sloan Kettering Cancer Center · USReproductive Medicine Associates of New York · USInstitute of Behavioral Sciences · JP

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

introductionPenile pain is one of the most stressful symptoms in men with Peyronie's disease (PD).

aimTo evaluate the prevalence, clinical presentation and risk factors associated with penile pain in men with PD as well as to assess the psychosocial impact.

methodsWe revised our institution's database of men diagnosed with PD. The information collected included penile pain assessments, and the scores of the PD Questionnaire (PDQ), Self-Esteem and Relationship Questionnaire (SEAR) and Center for Epidemiologic Studies Depression Scale Questionnaire (CES-D). Descriptive and comparative statistics were used. Logistic regression analyses were performed to evaluate predictive factors associated with penile pain.

main outcome measuresPenile pain descriptive assessment and factors associated with penile pain in men with PD. Comparison of SEAR, CES-D and PDQ domain scores of men with and without penile pain.

results431 men with PD were included for this analysis with a mean age of 55.9 years. Penile pain was reported by 36.7%; 65.2% of those had painful erection, 7% pain with flaccid state only, and 20% in both stages. The median pain severity was 3 with erection and 1 with flaccid stage. After adjusted logistic regression analyses, advanced age was associated with less pain (OR 0.94, P ≤ 0.001). Men with penile pain had no significant difference in CES-D and SEAR mean scores compared to men without penile pain. The PDQ scores for the physical/psychological symptoms domain and the bother domain were significantly higher in men with penile pain (12 vs 8.7; P < 0.01 and 9 vs 7.1; P < 0.01 respectively). Men with penile pain had a higher rate of clinically significant bother scores than men without penile pain (52% vs 35%, P ≤ 0.001).

conclusionPenile pain is common in men with PD. It was more common in young men and was associated with physical and psychological bothers in this population. Flores JM, Salter CA, Nascimento B, et al. The Prevalence and Predictors of Penile Pain in Men with Peyronie's Disease. Sex Med 2021;9:100398.

Indexed as

DepressionErectile DysfunctionPenile PainPeyronie's DiseaseSexual Dysfunction

Identifiers

PMID34246855
PMCPMC8360927
OpenAlexW3180179519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.