ArticleBMC geriatrics2021
Disability trajectories prior to death for ten leading causes of death among middle-aged and older adults in Taiwan.
Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07310849 (Digital Care Community Common Good Program Enhances Holistic Health Management for Middle Aged and Older Adults With Diabetes Mellitus and Multiple Chronic Conditions), which is not on this map. Cited by 8 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Digital Care Community Common Good Program Enhances Holistic Health Management for Middle Aged and Older Adults With Diabetes Mellitus and Multiple Chronic Conditions
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Functional decline in the final years of life: A multicohort study.BMC medicine · 2026Article
- A cross-sectional study to assess nutritional status among adolescents with disabilities in District Dehradun.Journal of family medicine and primary care · 2025Article
- Trends in palliative care utilization among older adult decedents with and without cancer in Taiwan: a population-based comparative study.The Lancet regional health. Western Pacific · 2025Article
- Disability during the last ten years of life: evidence from a register-based study in Austria.European journal of ageing · 2024Article
- Brain tumor segmentation using U-Net in conjunction with EfficientNet.PeerJ. Computer science · 2024Article
- Aging Affects Insulin Resistance, Insulin Secretion, and Glucose Effectiveness in Subjects with Normal Blood Glucose and Body Weight.Diagnostics (Basel, Switzerland) · 2023Article
- Trends and biopsychosocial correlates of physical disabilities among older men and women in Taiwan: examination based on ADL, IADL, mobility, and frailty.BMC geriatrics · 2022Article
- A Review of Clinical Signs and Symptoms of Imminent End-of-Life in Individuals With Advanced Illness.Gerontology & geriatric medicineReview
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundProlonged life expectancy is associated with increased prevalence of chronic diseases. The aim of this study was to determine the different disability trajectories for the top ten leading causes of death in Taiwan .
methodsA total of 2,431 participants aged 50-96 in 1996 from the Taiwan longitudinal study on aging (TLSA) who died from 1996 to 2016 were analyzed. Integration of Cause of Death Data and TLSA helped sort out participants who had died from the ten leading causes of death. The level of physical disability was evaluated with the Activities of Daily Living Scale (ADLs), ranging from 0 to 6 points, in 1996, 1999, 2003, 2007, and 2011. A multilevel model was used to investigate the levels and rates of change in disability development before death.
resultsThe outcome of the research showed that the earliest group to experience physical limitation was individuals living with diabetes. The groups with the highest ADL scores were participants with diabetes, cerebrovascular disease, and hypertension-related diseases. Most groups reach ADL scores ≥ 1 (mild-level) during 4-6 years before death except chronic hepatitis and cirrhosis and injury.
conclusionsPeople who had died from the ten leading causes of death experienced different disability trajectories before death. The trajectory of the participants who had died from diabetes showed a unique pattern with the earliest occurrence and more severe deterioration in terms of development of disabilities. Disability trajectories provide a prediction of survival status for middle-aged and older adults associated with the ten leading causes of death.
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