ArticleArchives of oral biology2021
Cariogenic and oral health taxa in the oral cavity among children and adults: A scoping review.
Article in Archives of oral biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Geraniol attenuates Streptococcus mutans biofilm and virulence as an anti-caries agent.Archives of microbiology · 2026Article
- DNA and RNA-based amplicon sequencing of paired supragingival and dentin lesion plaque in children with severe early childhood caries.International journal of oral science · 2026Article
- Oral Administration of Freeze-DriedFood science & nutrition · 2026Article
- Association of asthma and anti-asthmatic therapy with oral health and microbiota alterations in children - a cross-sectional study.BMC pediatrics · 2026Article
- Article
- Natural compounds: new therapeutic approach for inhibition ofFrontiers in pharmacology · 2025Review
- Saliva microbiome profiling by full-gene 16S rRNA Oxford Nanopore Technology versus Illumina MiSeq sequencing.NPJ biofilms and microbiomes · 2024Article
- ADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models.Bioinformatics (Oxford, England) · 2024Article
- Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses.BMC oral health · 2024Article
- Comparative analysis of microbiome in coronal and root caries.BMC oral health · 2024Article
- ADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models.bioRxiv : the preprint server for biology · 2024Article
- Salivary Diagnosis of Dental Caries: A Systematic Review.Current issues in molecular biology · 2024Review
- Antibacterial coating of orthodontic elastomeric ligatures with silver and bismuth nanofilms by magnetron sputtering: A feasibility study.Clinical and experimental dental research · 2024Article
- Plaque Microbiome in Caries-Active and Caries-Free Teeth by Dentition.JDR clinical and translational research · 2024Article
- Interactions and effects of a stannous-containing sodium fluoride dentifrice on oral pathogens and the oral microbiome.Frontiers in microbiology · 2024Article
- Mechanism of Action ofAntibiotics (Basel, Switzerland) · 2023Article
- Evaluating the ecological hypothesis: early life salivary microbiome assembly predicts dental caries in a longitudinal case-control study.Microbiome · 2022Article
- Oral Microbiome and Dental Caries Development.Dentistry journal · 2022Review
- Susceptibility of Dental Caries Microcosm Biofilms to Photodynamic Therapy Mediated by Fotoenticine.Pharmaceutics · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo review published oral microbiome studies and create a comprehensive list of bacterial species found in saliva and dental plaque among healthy children and adults associated with presence of carious lesions and caries-free state (oral health).
designThis review followed PRISMA-ScR guidelines. We searched published studies querying PUBMED and EMBASE using the following keywords: (plaque OR saliva) AND caries AND (next generation sequencing OR checkerboard OR 16s rRNA or qPCR). Studies were limited to human studies published in English between January 1, 2010 and June 24, 2020 that included > 10 caries-active and > 10 caries-free participants, and assessed the entire bacterial community.
resultsOur search strategy identified 298 articles. After exclusion criteria, 22 articles remained; we considered 2 studies that examined saliva and plaque as separate studies, for a total of 24 studies. Species associated with caries or oral health varied widely among studies reviewed, with notable differences by age and biologic sample type. No bacterial species was associated with caries in all studies. Streptococcus mutans was found more frequently among those with caries (14/24 (58.3 %)) and Fusobacterium periodonticum was found more frequently among those that were caries-free (5/24 (20.8 %)).
conclusionNo bacterial species was associated with caries or oral health across all studies supporting multiple pathways to cariogenesis. However, the variation may be due to sampling at different time points during caries development, varying methods of specimen sampling, storage, sequencing or analysis or differences in host factors such as age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.