ArticleSchizophrenia research2021
Self-harm, suicidal ideation, and the positive symptoms of psychosis: Cross-sectional and prospective data from a national household survey.
Article in Schizophrenia research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- An umbrella review synthesising published systematic review evidence for self-harm and suicidality among patients diagnosed with an eating or feeding disorder.BMC psychology · 2026Pooled it
- Psychotic Experiences and Risk of Suicidal Thoughts and Behaviors: A Systematic Review and Meta-Analysis of Longitudinal Population Studies.Schizophrenia bulletin · 2026Pooled it
- An update meta-analysis on the relationship between psychotic experiences and self-injurious thoughts and behaviors in children and adolescents.European child & adolescent psychiatry · 2025Pooled it
- Machine learning and the prediction of suicide in psychiatric populations: a systematic review.Translational psychiatry · 2024Pooled it
- Psychosocial Interventions, Recovery, and Mediating Mechanisms in Schizophrenia-Spectrum Disorders: A Systematic Review and Meta-Analysis of Longitudinal Studies.Brain sciences · 2026Review
- Shared and distinct features between interpersonal and self-directed violent behaviors: a simulated intervention network study.BMC public health · 2026Article
- Specific psychological factors associated with suicidal ideation: a transdiagnostic approach to psychological responses in adolescents.BMC psychology · 2026Article
- Adapting a Suicide Prevention Program for People with Psychosis Following a Psychiatric Hospitalization: Pilot Results and Lessons Learned.International journal of cognitive behavioral therapy · 2025Article
- Treatment Preferences in Acute Psychosis: A Comparison of Patient and Staff Perspectives on Symptom Prioritization and Biopsychosocial Interventions.The Psychiatric quarterly · 2025Article
- Suicidal ideation in Chinese patients with chronic schizophrenia: prevalence, clinical correlates, and relationship with alexithymia.European archives of psychiatry and clinical neuroscience · 2024Article
- The Role of Verbal Auditory Hallucinations in Influencing and Retrospectively Predicting Physical Harm Prevalence in Early Psychosis.Clinical practice and epidemiology in mental health : CP & EMH · 2024Article
- Strengthening associations between psychotic like experiences and suicidal ideation and behavior across middle childhood and early adolescence.Psychological medicine · 2023Article
- Metabolic parameters and thyroid hormones in relation to suicide attempts in patients with first-episode and drug-naive major depressive disorder with comorbid glucose disturbances: a large cross-sectional study.European archives of psychiatry and clinical neuroscience · 2023Article
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundSchizophrenia is associated with premature mortality, partly through increased suicide rates.
aimsTo examine (1) if persecutory ideas, auditory hallucinations, and probable cases of psychosis are associated with suicidal thoughts or attempts cross-sectionally and prospectively, and (2) if such links are mediated by specific affective factors (depression, impulsivity, mood instability).
methodWe analysed the 2000, 2007, and 2014 British Adult Psychiatric Morbidity Surveys (APMS) separately. Measures of psychosis provided independent variables for multi-stage logistic regressions, with suicidal thoughts and attempts as dependent variables. We also conducted analyses to assess mediation by affective variables, and longitudinal analyses on a subset of the 2000 dataset.
resultsIn every dataset, persecutory ideas, auditory hallucinations and probable psychosis were associated cross-sectionally with lifetime suicidal attempts and thoughts, even after controlling for confounders, with a single exception (persecutory ideation and suicide attempts were unconnected in APMS 2014). Cross-sectional associations between auditory hallucinations and suicidal phenomena were moderated by persecutory ideation. In the 2000 follow-up, initial persecutory ideas were associated with later suicidal thoughts (O.R. 1.77, p < 0.05); there were no other longitudinal associations. In the 2007 and 2014 datasets, mood instability mediated the effects of psychotic phenomena on suicidality more strongly than impulsivity; depression was also an important mediator. There were appreciable direct effects of positive symptoms on suicidal thoughts and behaviour.
conclusionsImproving psychotic symptoms and ameliorating co-morbid distress may in itself be effective in reducing suicidal risk in schizophrenia. Given their potential mediating role, mood instability and depression may also be targets for intervention.
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