ArticleDrug and alcohol dependence2021
Cohort and age trends in age 35-45 prevalence of alcohol use disorder symptomology, by severity, sex, race, and education.
Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Alcohol use disorder diagnoses among commercially insured US adults from 2016 to 2023, by disability status and sex.Drug and alcohol dependence reports · 2026Article
- Gonadal Sex and Sex-Chromosome Complement Interact to Affect Ethanol Consumption in Adolescent Four Core Genotypes Mice.Brain sciences · 2026Article
- Maturing out or in? Demographic determinants of young adult drinking trajectories and midlife alcohol use disorder risks.Alcohol, clinical & experimental research · 2026Article
- Alcohol Use Disorder in Southwestern and Northern Uganda: Prevalence and associated factors.PLOS global public health · 2026Article
- Trends in alcohol use disorder symptoms among U.S. adults disaggregated by sex, race, and age.Social psychiatry and psychiatric epidemiology · 2025Article
- Prevalence and longitudinal effects on mortality associated with spectrum of alcohol intake in steatotic liver disease: a United States population study.Hepatobiliary surgery and nutrition · 2025Article
- Longitudinal analysis of the ABCD® study.Developmental cognitive neuroscience · 2025Review
- Links between adolescent binge drinking and midlife alcohol use behaviors by age, sex, and race/ethnicity.Alcohol, clinical & experimental research · 2024Article
- Cohort effects of women's mid-life binge drinking and alcohol use disorder symptoms in the United States: Impacts of changes in timing of parenthood.Addiction (Abingdon, England) · 2023Article
- Age- and Sex-Varying Associations Between Depressive Symptoms and Substance Use from Modal Ages 35 to 55 in a National Sample of U.S. Adults.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Alcohol Use Disorder Symptoms Reported during Midlife: Results from the Monitoring the Future Study among US Adults at Modal Ages 50, 55, and 60.Substance use & misuse · 2023Article
- The destabilization and destandardization of social roles across the adult life course: Considering aggregate social role instability and its variability from a historical-developmental perspective.Developmental psychology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
aimsTo present national trends by age and cohort among middle-aged adults in the prevalence of AUD symptomology, by severity, sex, race, and education.
designNational, multi-cohort longitudinal probability samples of US adults, with data collected at ages 35, 40, and 45 among 14 cohorts who reached age 45 between 2003 and 2016.
settingData were collected via self-administered questionnaires to adults in the United States.
participantsThe sample consisted of 20,634 individuals. MEASUREMENTS: 5-year prevalence of symptoms consistent with a DSM-5 AUD.
findingsBetween ages 35-45 prevalence of any AUD symptoms decreased 19 %; decreases were most evident between ages 35-40. From 2003 to 2016, AUD symptoms were steady across cohort. However, because the pace of decrease across ages 35-45 slowed across cohort, cohort differences emerged at specific ages: age 35 prevalence decreased 18 % across cohort, but age 45 prevalence was equivalent across cohort. Age and cohort effects, and their interaction, did not vary by AUD severity level. Declines in AUD symptoms across age were 17 % slower for women, and declines in AUD symptoms across age and cohort were 11 % and 29 % slower, respectively, for those with a college degree. The protection afforded by a college degree was reversed among mild AUD and most pronounced for severe AUD.
conclusionsAUDs may be more plastic and responsive to intervention during early mid-life than later. Despite progress in reducing the burden of AUD in the US population among younger middle-aged adults, an increased focus remains necessary as they continue to age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.