Evidence map›Paper›PMID 34245409›Full record

ReviewMolecular biology reports2021

Neuroregulatory role of ginkgolides.

Martyna Gachowska, Wojciech Szlasa, Jolanta Saczko, Julita Kulbacka

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  7. Network-Based Identification ofCurrent pharmaceutical design · 2026
    Article
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  15. Article
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  18. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Martyna GachowskaFaculty of Medicine, Wroclaw Medical University, Wrocław, Poland.ORCID http://orcid.org/0000-0003-0749-2098
Wojciech SzlasaFaculty of Medicine, Wroclaw Medical University, Wrocław, Poland.ORCID http://orcid.org/0000-0002-5477-5771
Jolanta SaczkoDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland.ORCID http://orcid.org/0000-0001-5273-5293
Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland. Julita.Kulbacka@umed.wroc.pl.ORCID http://orcid.org/0000-0001-8272-5440
Wroclaw Medical University · PL

Funding

Statutory Funds SUB.D.260.21.095
6 · The paper itself

Abstract

The application of ginkgolides as a herbal remedy reaches ancient China. Over time many studies confirmed the neuroprotective effect of standard Ginkgo biloba tree extract-the only available ginkgolide source. Ginkgolides present a wide variety of neuroregulatory properties, commonly used in the therapy process of common diseases, such as Alzheimer's, Parkinson's, and many other CNS-related diseases and disorders. The neuroregulative properties of ginkgolides include the conditioning of neurotransmitters action, e.g., glutamate or dopamine. Besides, natural compounds induce the inhibition of platelet-activating factors (PAF). Furthermore, ginkgolides influence the inflammatory process. This review focuses on the role of ginkgolides as neurotransmitters or neuromodulators and overviews their impact on the organism at the molecular, cellular, and physiological levels. The clinical application of ginkgolides is discussed as well.

Indexed as

AnimalsBiomarkersClinical Studies as TopicDisease ManagementDrug Evaluation, PreclinicalDrugs, Chinese HerbalGinkgo bilobaGinkgo ExtractGinkgolidesHumansImmunomodulationNeuronsNeuroprotective AgentsNeurotransmitter AgentsPlant ExtractsTreatment OutcomeBiomarkersDrugs, Chinese HerbalGinkgo biloba extractGinkgo ExtractGinkgolidesNeuroprotective AgentsNeurotransmitter AgentsPlant ExtractsGinkgo bilobaGinkgolidesNeuroprotectionNeuro-regulation

Identifiers

PMID34245409
PMCPMC8338821
OpenAlexW3179416772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.