Evidence map›Paper›PMID 34245408›Full record

ArticleOral radiology2022

A comparative study on cephalometric differences in maxillofacial morphology between skeletal Class III cases with and without acromegaly: a pilot study.

Atsushi Tanaka, Noriaki Shoji, Ikuho Kojima, Akira Kumasaka, Maya Sakamoto, Kiyo Sasaki, Tomohiro Fukunaga, Itaru Mizoguchi, Teiji Tominaga, Masahiro Iikubo

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Article in Oral radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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10 authors.

Atsushi TanakaDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
Noriaki ShojiDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan. shoji_noriaki@dent.tohoku.ac.jp.ORCID http://orcid.org/0000-0002-3192-9248
Ikuho KojimaDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
Akira KumasakaDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
Maya SakamotoDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
Kiyo SasakiDivision of Orthodontics and Dentofacial Orthopaedics, Tohoku University Graduate School of Dentistry, Aoba-ku, Sendai, Japan.
Tomohiro FukunagaDivision of Orthodontics and Dentofacial Orthopaedics, Tohoku University Graduate School of Dentistry, Aoba-ku, Sendai, Japan.
Itaru MizoguchiDivision of Orthodontics and Dentofacial Orthopaedics, Tohoku University Graduate School of Dentistry, Aoba-ku, Sendai, Japan.
Teiji TominagaDepartment of Neurosurgery, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan.
Masahiro IikuboDivision of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe most typical maxillofacial feature of patients with acromegaly is mandibular protrusion. This study aimed to determine differences in maxillofacial morphology between skeletal Class III patients with and without acromegaly using cephalometric analysis.

methodsCephalograms of 37 patients with acromegaly (Acro), 37 age-matched non-acromegalic patients with skeletal Class III malocclusion (C-III), and 37 age-matched Class I malocclusion patients (C-I; control) were retrospectively collected. The skeletal and dental morphology of each group was analyzed using cephalometric analysis, which included linear and angular measurements and facial profilograms. In addition, we analyzed diagnostic performance and cutoff values for discriminating acromegaly from skeletal Class III malocclusion using receiver operating characteristic (ROC) curve analysis.

resultsThe mandibular ramus height was larger in the Acro group than in the other groups. The increase in L1/MP in the Acro group, which represented labial inclination of the mandibular central incisors, was the most characteristic feature in this study. ROC curve analysis indicated that a cutoff value of 88.4° for L1/MP had the highest diagnostic performance in discriminating acromegaly from non-acromegalic Class III malocclusion.

conclusionsAcromegaly was characterized by a greater degree of bimaxillary prognathism than was non-acromegalic Class III malocclusion. Focusing on labial inclination of the mandibular central incisors would be the most useful way to differentiate acromegaly from non-acromegalic Class III malocclusion.

Indexed as

AcromegalyMalocclusion, Angle Class IIICephalometryHumansPilot ProjectsRetrospective StudiesAcromegalyCephalometric analysisMandibular prognathismNon-acromegalic patientsSkeletal Class III malocclusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.