Evidence map›Paper›PMID 34245378›Full record

ArticlePflugers Archiv : European journal of physiology2021

The role of adrenergic and muscarinic receptors in stress-induced cardiac injury.

Boris K Kurbatov, Ekaterina S Prokudina, Leonid N Maslov, Natalia V Naryzhnaya, Sergey V Logvinov, Alexander S Gorbunov, Alexandr V Mukhomedzyanov, Andrey V Krylatov, Nikita S Voronkov, Andrey S Sementsov and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of β-Adrenergic Receptors in Stress-Induced Cardiac Injury.Bulletin of experimental biology and medicine · 2025
    Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Boris K KurbatovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Ekaterina S ProkudinaLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Leonid N MaslovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Natalia V NaryzhnayaLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia. natalynar@yandex.ru.ORCID 0000-0003-2264-1928
Sergey V LogvinovDepartment of Histology, Embryology and Cytology, Siberian State Medical University, 634055, Tomsk, Russia.
Alexander S GorbunovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Alexandr V MukhomedzyanovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Andrey V KrylatovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Nikita S VoronkovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Andrey S SementsovLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Konstantin V ZavadovskyLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Viktor V SaushkinLaboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, 634012, Tomsk, Russia.
Rajendra P NagarajanDepartment of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, 608002, Tamilnadu, India.
Peter R OeltgenDepartment of Pathology, University of Kentucky, College of Medicine, Lexington, KY, USA.
Russian Academy of Sciences · RUAnnamalai University · INSiberian State Medical University · RUUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo syndrome (TS) is a rare but dangerous disease that can be fatal. The pathogenesis of TS is not well understood because there is no animal model of TS that fully mimics TS. It has now been documented that stress exposure (24 h) of rats induced the state which is similar TS in human: contracture damage of myofibrils, elevation of the serum creatine kinase MB level, increased

Indexed as

Stress, PhysiologicalAnimalsArginineCorticosteroneFemaleHeart InjuriesMaleNatriuretic Peptide, BrainOrgan SizeRatsRats, WistarReceptors, AdrenergicReceptors, MuscarinicSpleenArginineCorticosteroneNatriuretic Peptide, BrainN,N-dimethylarginineReceptors, AdrenergicReceptors, MuscarinicAdrenergic receptorsGlucocorticoidsReactive oxygen speciesStress-induced cardiac injuryTakotsubo syndrome

Identifiers

PMID34245378
OpenAlexW3179637830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.