Evidence map›Paper›PMID 34245371›Full record

ArticleJournal of cancer research and clinical oncology2022

The prognostic role of radiotherapy and radiotherapy target in cervical lymph node metastatic squamous cell carcinoma with unknown primary: a retrospective study.

Ruidan Li, Kai Liao, Zhigong Wei, Zheran Liu, Yan He, Jingjing Wang, Ling He, Xiaoli Mu, Lianlian Yang, Yan Huang and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer research and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ruidan Li *The State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Kai Liao *Department of Radiology, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan, People's Republic of China.
Zhigong WeiThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Zheran LiuThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Yan HeThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Jingjing WangThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Ling HeThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Xiaoli MuThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Lianlian YangThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Yan HuangThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China.
Libang HeState Key Laboratory of Oral Diseases, Department of Cariology and Endodontics, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China. helibang@163.com.
Xingchen PengThe State Key Laboratory of Biotherapy, Department of Biotherapy, Cancer Center, West China Hospital, West China Medical School, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, Sichuan, People's Republic of China. pxx2014@163.com.ORCID http://orcid.org/0000-0001-7042-718X
Sichuan University · CN

Funding

National Natural Science Foundation of China 81402494National Natural Science Foundation of China 81672386Sichuan Province Science and Technology Support Program No.2021YFSY008the technology Innovation Project of Chengdu Science and Technology Bureau No.2019-YF05-00459-SN
6 · The paper itself

Abstract

objectivesAim to analyze the effect of radiotherapy for cervical lymph node metastatic carcinoma with unknown primary (CCUP) and compare the survival benefits between Comprehensive radiotherapy and Involved Field radiotherapy. MATERIALS AND

methodsThe patients diagnosed with CCUP between 2009 and 2019 in our institution were analyzed retrospectively. The categorical variables were tested by χ

resultsOf 139 patients, 64.7% (90/139) of them received radiotherapy. Of the 90 patients who underwent radiotherapy, 45.6% (41/90) received Involved Field radiotherapy and the rest 49 patients received Comprehensive radiotherapy. The median follow-up of 139 patients is 69 months. The 1-year, 3-year, and 5-year OS rates are 87%, 62%, and 39%, respectively, and the DFS rates are 73%, 45%, and 29%, respectively. Multivariate analysis of 139 patients with CCUP shows that differentiation grade, N stage, radiotherapy, and the length of the largest lymph node (D

conclusionRadiotherapy is the independent prognostic factor for CCUP. Comprehensive radiotherapy may be superior to Involved Field radiotherapy in survival benefits.

Indexed as

Carcinoma, Squamous CellNeoplasms, Unknown PrimaryHumansLymphatic MetastasisLymph NodesNeoplasm StagingPrognosisRetrospective StudiesCervical lymph node metastatic carcinoma with unknown primaryPrognosisRadiotherapyTarget delineation

Identifiers

PMID34245371
PMCPMC11801032
OpenAlexW3178286939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.