ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
Sleep problems and their interaction with physical activity and fatigue in hematological cancer patients during onset of high dose chemotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The role of wearable technologies in supporting physical and psychosocial health outcomes among breast cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Impact on fatigue of different types of physical exercise during adjuvant chemotherapy and radiotherapy in breast cancer: systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Sleep and spa therapies: What is the role of balneotherapy associated with exercise? A systematic review.Frontiers in physiology · 2022Pooled it
- The efficacy of lavender oil on fatigue and sleep quality in patients with hematological malignancy receiving chemotherapy: a single-blind randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Study on the Conduction Analysis and Blocking Intervention Scheme of Emotional Disorders between Cancer Patients and Their Families.Computational and mathematical methods in medicine · 2022Trial
- Sleep quality and sleepiness in adults with multiple myeloma. Is melatonin a potential treatment?Physiological reports · 2026Observational
- Translating Patient Experiences Into Multimethod Assessment and Evidence-Based Care: Next Steps in Research on Sleep Disturbance in Acute Leukemia [Letter].Journal of multidisciplinary healthcare · 2025Article
- Sleep Disorders in Young and Middle-Aged Adults with Acute Leukemia Undergoing Chemotherapy: A Qualitative Study from a Biopsychosocial Perspective.Journal of multidisciplinary healthcare · 2025Article
- Similarities and important distinctions between drug and behavioral intervention development.Discover psychology · 2025Review
- Quality of Life and Symptoms of Hospitalized Hematological Cancer Patients.Current oncology (Toronto, Ont.) · 2024Article
- Managing sleep disruptions during cancer: Practical tips for patient education.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024Article
- A nationally representative study of aerobic activity and strength training in older cancer survivors and their psychological distress and sleep difficulties.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Repeated automatic sleep scoring based on ear-EEG is a valuable alternative to manually scored polysomnography.PLOS digital health · 2022Article
- Physical activity and sleep behaviour in women carrying BRCA1/2 mutations.Scientific reports · 2022Article
- The relationship between sleep hygiene, mood, and insomnia symptoms in men with prostate cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Exercise improves health-related quality of life sleep and fatigue domains in adult high- and low-grade glioma patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Short Sleep Duration as a Risk Factor for Depression, Anxiety and Fatigue in Patients with Leukemia.Neuropsychiatric disease and treatment · 2022Article
- Mindful Night-to-Day: A Pilot Feasibility Trial of a Mindfulness-Based Insomnia and Symptom Management Intervention for Patients with Hematologic Cancer.Behavioral sleep medicineArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSleep problems reported by hematological cancer patients are usually linked to higher levels of cancer-related fatigue. Although the awareness of sleep problems in solid cancer patients is rising, there has been less attention to the issue in hematological cancer patients. The present study assesses the differences in sleep by comparing physical activity and fatigue levels among hematological cancer patients during the onset of chemotherapy. Furthermore, it investigates the relationship between sleep, physical activity, and fatigue through mediation analysis.
methodsThe recruited sample consists of 58 newly diagnosed hematological cancer patients (47.1 ± 15.4 yrs; 51.7% males). Subjects completed questionnaires assessing sleep (PSQI), physical activity (visual analogue scale), fatigue (MFI-20), anxiety, depression (HADS), and quality of life (EORTC QLQ-C30) within two weeks from starting treatment.
resultsThe sample reported more sleep problems in comparison to the German population norm. The classification as good (ca 25%) or bad sleepers (ca 75%) showed less frequent physical activity (p = .04), higher fatigue (p = .032), anxiety (p = .003), depression (p = .011) and pain (p = .011) in bad sleepers. The mediation analysis revealed significant indirect effects of sleep on fatigue through physical activity habits.
conclusionsThis study highlights the combined action of sleep problems and physical activity on fatigue during the onset of induction chemotherapy. These two parameters could represent meaningful intervention targets to improve a patient's status during chemotherapy.
trial registrationThe study was registered on the WHO trial register (DRKS00007824).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.