Evidence map›Paper›PMID 34245223›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

First World Consensus Conference on pancreas transplantation: Part II - recommendations.

Ugo Boggi, Fabio Vistoli, Axel Andres, Helmut P Arbogast, Lionel Badet, Walter Baronti, Stephen T Bartlett, Enrico Benedetti, Julien Branchereau, George W Burke and 66 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Review
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  10. Article
  11. Impact of Induction Therapy in Low Immunological Risk Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  12. Simultaneous Pancreas-Kidney Versus Kidney Transplant Alone: Real-World Outcomes in a Propensity-Matched Global Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  13. Duodenoduodenostomy as an Attractive Option for Exocrine Drainage in Pancreas Transplantation: Insights From a Single-Center Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  14. Review
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  20. Tacrolimus's Time Below Therapeutic Range Is Associated With Acute Pancreatic Graft Rejection and the Development ofTransplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

76 authors at 20 institutions in 16 countries.

Ugo BoggiDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0002-7505-5896
Fabio VistoliDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0003-2115-4191
Axel AndresDivision of Transplantation, Department of Surgery, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-3329-0801
Helmut P ArbogastDepartment of General, Visceral and Transplant Surgery, Grosshadern Medical Centre, University of Munich, Munich, Germany.ORCID 0000-0001-5410-8699
Lionel BadetDepartment of Urology and Transplantation, E. Herriot Hospital/Lyon 1 University, Lyon, France.ORCID 0000-0002-9596-0279
Walter BarontiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-4532-3028
Stephen T BartlettDivision of Transplantation, Department of Surgery, University of Maryland Medical Center, Baltimore, Maryland, USA.ORCID 0000-0002-3980-2559
Enrico BenedettiDepartment of Surgery, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-1120-6058
Julien BranchereauDepartment of Urology, Nantes University Hospital, CHU de Nantes, Nantes, France.ORCID 0000-0002-8460-9352
George W BurkeDivision of Kidney-Pancreas Transplantation, Department of Surgery, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami Transplant Institute, Miami, Florida, USA.ORCID 0000-0002-6888-2842
Fanny BuronDepartment of Transplantation, Nephrology and Clinical Immunology, Hospital/Lyon 1 University, Lyon, France.ORCID 0000-0003-0404-6746
Rossana CaldaraInternal Medicine and Transplantation, Scientific Institute San Raffaele, Milan, Italy.ORCID 0000-0001-7115-5681
Massimo CardilloItalian National Transplant Center, Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0002-2776-2297
Daniel CasanovaDepartment Surgery, University of Cantabria, Santander, Spain.ORCID 0000-0003-3863-5039
Federica CiprianiHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-8651-5982
Matthew CooperMedstar Georgetown Transplant Institute, Washington, DC, USA.ORCID 0000-0002-3438-9638
Adamasco CupistiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-8995-936X
Josè DavideDivision of Transplantation, Centro Hospitalar Universitário do Porto, Institute of Biomedical Sciences Abel Salazar, University of Porto and Pancreas Transplantation Program, Porto, Portugal.ORCID 0000-0003-3174-2456
Cinthia DrachenbergDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3104-5661
Eelco J P de KoningDepartment of Medicine and Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-1232-7022
Giuseppe Maria EttorreTransplantation Department, S. Camillo-Forlanini Hospital, Rome, Italy.ORCID 0000-0002-7501-5472
Laureano Fernandez CruzHospital Clinic University of Barcelona, Barcelona, Spain.ORCID 0000-0001-5652-1209
Jonathan A FridellDepartment of Surgery, Indiana University, Indianapolis, Indiana, USA.ORCID 0000-0002-8708-1506
Peter J FriendNuffield Department of Surgical Sciences, University of Oxford, Oxford, England, UK.ORCID 0000-0003-0841-9685
Lucrezia FurianKidney and Pancreas Transplantation Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.ORCID 0000-0002-2264-7986
Osama A GaberJ.C. Walter Jr. Center for Transplantation, Department of Surgery, Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0002-9444-3202
Angelika C GruessnerDepartment of Medicine, SUNY Downstate Medical Center, The State University of New York, Brooklyn, New York, USA.ORCID 0000-0001-5961-5913
Rainer W G GruessnerDepartment of Surgery, SUNY Downstate Medical Center, The State University of New York, Brooklyn, New York, USA.ORCID 0000-0002-2094-9817
Jenny E GuntonCentre for Diabetes, Obesity and Endocrinology, Westmead Institute for Medical Research, Westmead, Australia.ORCID 0000-0002-8127-9773
Duck-Jong HanTransplantation Department, Asan Medical Center, Ulsan University, Seoul, South Korea.ORCID 0000-0002-0990-6824
Sara IacopiDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.
Emanuele Federico KauffmannDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0001-7634-4844
Dixon KaufmanDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0003-3615-0994
Takashi KenmochiDepartment of Organ Transplant Surgery, Fujita Health University, Toyoake, Japan.ORCID 0000-0002-9090-8770
Hussein A KhambaliaDepartment of Transplantation, Manchester Foundations Hospitals NHS Foundation Trust, Manchester Royal Infirmary, Manchester, UK.ORCID 0000-0002-7553-3026
Quirino LaiGeneral Surgery and Orgn Transplantation Unit, Sapienza University of Rome, Umberto I Polyclinico of Rome, Rome, Italy.ORCID 0000-0003-1487-3235
Robert M LangerOrdensklinikum Elisabethinen, University of Linz, Linz, Austria.ORCID 0000-0001-8349-1260
Paola MaffiInternal Medicine and Transplantation, Scientific Institute San Raffaele, Milan, Italy.ORCID 0000-0001-5011-6499
Lorella MarselliDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-6698-2962
Francesco MenichettiInfectious Disease Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0003-0824-7166
Mario MiccoliDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-8632-6145
Shruti MittalNuffield Department of Surgical Sciences, University of Oxford, Oxford, England, UK.ORCID 0000-0003-2390-5366
Emmanuel MorelonDepartment of Transplantation, Nephrology and Clinical Immunology, Hospital/Lyon 1 University, Lyon, France.ORCID 0000-0001-9928-1671
Niccolò NapoliDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0003-2538-9158
Flavia NeriKidney and Pancreas Transplantation Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.ORCID 0000-0002-2677-8967
Jose OberholzerDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-1069-2501
Jon S OdoricoDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0003-1096-464X
Robert ÖllingerDepartment of Surgery, Campus Charité-Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-4499-1673
Gabriel OniscuEdinburgh Transplant Centre, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, Scotland, UK.ORCID 0000-0003-1714-920X
Giuseppe OrlandoDepartment of Surgery, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0002-6460-7974
Monica OrtenziDepartment of General and Emergency Surgery, Polytechnic University of Marche, Ancona, Italy.ORCID 0000-0002-6508-6488
Marcelo PerosaPancreas Transplant Program, Abdominal Organ Transplantation Department, Leforte Hospital Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0002-8576-9761
Vittorio Grazio PerroneDivision of General and Transplant Surgery, University of Pisa, Pisa, Italy.
Henry PleassDepartment of Surgery, Weastmead Clinical School, University of Sydney, Sydney, Australia.ORCID 0000-0002-9814-0452
Robert R RedfieldDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0001-5986-3466
Claudio RicciDepartment of Internal Medicine and Surgery, University of Bologna, Bologna, Italy.ORCID 0000-0002-6638-4479
Paolo RigottiKidney and Pancreas Transplantation Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.ORCID 0000-0002-8895-935X
R Paul RobertsonDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Washington, Seattle, Washington, USA.
Lainie F RossMacLean Center for Clinical Medical Ethics, Departments of Pediatrics, Medicine and Surgery, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-7395-3000
Massimo RossiGeneral Surgery and Orgn Transplantation Unit, Sapienza University of Rome, Umberto I Polyclinico of Rome, Rome, Italy.ORCID 0000-0001-5105-4656
Frantisek SaudekDiabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.ORCID 0000-0002-0448-4351
Joseph R ScaleaDivision of Transplantation, Department of Surgery, University of Maryland Medical Center, Baltimore, Maryland, USA.ORCID 0000-0001-8278-2859
Peter SchenkerDepartment of Surgery, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0002-3607-6993
Antonio SecchiInternal Medicine and Transplantation, Scientific Institute San Raffaele, Milan, Italy.ORCID 0000-0002-4208-5116
Carlo SocciDepartment of Surgery, Scientific Institute San Raffaele, Milan, Italy.ORCID 0000-0002-3276-5556
Donzilia Sousa SilvaDivision of Transplantation, Centro Hospitalar Universitário do Porto, Institute of Biomedical Sciences Abel Salazar, University of Porto and Pancreas Transplantation Program, Porto, Portugal.ORCID 0000-0002-7165-3581
Jean Paul SquiffletDepartment of Abdominal Surgery and Transplantation, University of Liege, Liege, Belgium.ORCID 0000-0002-0467-7559
Peter G StockDivision of Transplantation, Department of Surgery, University of California at San Francisco, San Francisco, California, USA.ORCID 0000-0002-5806-0167
Robert J StrattaDepartment of Surgery, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0001-7634-094X
Chiara TerrenzioDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-0629-2134
Pablo UvaKidney Pancreas Transplantation, Instituto de Trasplantes y Alta Complejidad (ITAC - Nephrology), Buenos Aires, Argentina.ORCID 0000-0001-7317-3875
Christopher J E WatsonDepartment of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, England, UK.ORCID 0000-0002-0590-4901
Steven A WhiteDepartment of Hepato-pancreatico-biliary and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne, England, UK.
Piero MarchettiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0003-4907-0635
Raja KandaswamyDepartment of Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0003-4302-0119
Thierry BerneyDivision of Transplantation, Department of Surgery, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-4230-9378
University of Pisa · ITSan Raffaele University of Rome · ITUniversité Claude Bernard Lyon 1 · FRUniversity of Maryland, Baltimore · USUniversity of Padua · ITUniversity of Wisconsin–Madison · USPoliclinico Umberto I · ITState University of New York · USUniversidade do Porto · PTUniversity of Geneva · CHUniversity of Oxford · GBWake Forest University · USAsan Medical Center · KRCarlo Forlanini Hospital · ITCentre Hospitalier Universitaire de Nantes · FRCharité - Universitätsmedizin Berlin · DEEdinburgh Royal Infirmary · GBFreeman Hospital · GBFujita Health University · JPHospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts' recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.

Indexed as

Diabetes Mellitus, Type 1Kidney TransplantationPancreas TransplantationGraft SurvivalHumansQuality of LifeRenal Dialysisclinical research/practicediabetespancreas/simultaneous pancreas-kidney transplantationsurvey

Identifiers

PMID34245223
PMCPMC8518376
OpenAlexW3182737744

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.