Evidence map›Paper›PMID 34245131›Full record

ArticleCancer reports (Hoboken, N.J.)2021

Peripheral blood stem cell mobilization with pegylated granulocyte colony stimulating factor in children.

Dhwanee Thakkar, Aseem K Tiwari, Swati Pabbi, Rohit Kapoor, Geet Aggarwal, Neha Rastogi, Satya Prakash Yadav

Open access · goldAbstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dhwanee ThakkarDepartment of Pediatric Hematology Oncology and BMT, Medanta The Medicity, Gurgaon, India.
Aseem K TiwariDepartment of Transfusion Medicine, Medanta The Medicity, Gurgaon, India.
Swati PabbiDepartment of Transfusion Medicine, Medanta The Medicity, Gurgaon, India.
Rohit KapoorDepartment of Pediatric Hematology Oncology and BMT, Medanta The Medicity, Gurgaon, India.
Geet AggarwalDepartment of Transfusion Medicine, Medanta The Medicity, Gurgaon, India.
Neha RastogiDepartment of Pediatric Hematology Oncology and BMT, Medanta The Medicity, Gurgaon, India.ORCID 0000-0003-4699-6723
Satya Prakash YadavDepartment of Pediatric Hematology Oncology and BMT, Medanta The Medicity, Gurgaon, India.ORCID 0000-0002-0507-1786
Medanta The Medicity · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimWe report here our experience of using pegylated granulocyte colony stimulating factor (peg-GCSF) for peripheral blood stem cell (PBSC) mobilization in children. METHODS AND

resultsA total of nine children suffering from high-risk/relapsed solid tumors were mobilized with chemotherapy and peg-GCSF (100 microgram/kg single dose). Mean age was 7.7 years (range 2-15 years).The mean time from peg-GCSF administration to PBSC harvest was 9.7 days. Adequate stem cells (median dose 26.9 million/kg) could be harvested in all children by a single apheresis procedure. No major adverse events observed.

conclusionIt is feasible and safe to mobilize PBSC with peg-GCSF in children with cancer.

Indexed as

AdolescentAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolCombined Modality TherapyFemaleFollow-Up StudiesGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationHumansMaleNeoplasmsPeripheral Blood Stem CellsPolyethylene GlycolsPrognosisGranulocyte Colony-Stimulating Factorpegylated granulocyte colony-stimulating factorPolyethylene GlycolsRecombinant Proteinschildrenmobilizationpegylated-GCSFperipheral blood stem cell

Identifiers

PMID34245131
PMCPMC8714533
OpenAlexW3179034084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.